Biological Effects of Space Hypomagnetic Environment on Circadian Rhythm.

Front Physiol

State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou, China.

Published: March 2021

The intrinsic earth magnetic field (geomagnetic field, GMF) provides an essential environmental condition for most living organisms to adapt the solar cycle by rhythmically synchronizing physiological and behavioral processes. However, hypomagnetic field (HMF) of outer space, the Moon, and the Mars differs much from GMF, which poses a critical problem to astronauts during long-term interplanetary missions. Multiple experimental works have been devoted to the HMF effects on circadian rhythm and found that HMF perturbs circadian rhythms and profoundly contributes to health problems such as sleep disorders, altered metabolic as well as neurological diseases. By systemizing the latest progress on interdisciplinary cooperation between magnetobiology and chronobiology, this review sheds light on the health effects of HMF on circadian rhythms by elaborating the underlying circadian clock machinery and molecular processes.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7985258PMC
http://dx.doi.org/10.3389/fphys.2021.643943DOI Listing

Publication Analysis

Top Keywords

circadian rhythm
8
circadian rhythms
8
circadian
5
biological effects
4
effects space
4
space hypomagnetic
4
hypomagnetic environment
4
environment circadian
4
rhythm intrinsic
4
intrinsic earth
4

Similar Publications

The clinical impact of chronopharmacology on current medicine.

Naunyn Schmiedebergs Arch Pharmacol

January 2025

Department of Pharmacology, School of Medicine, Marmara University, Istanbul, Turkey.

One of the goals of clinical pharmacology is to optimize patient treatment by adopting new treatment strategies which will increase the efficacy of the treatment and decrease the adverse effects of the drugs. In the literature, it has shown that the effectiveness and toxicity of medications can vary significantly based on when they are administered, making timing a crucial factor in treatment plans. Chronopharmacology a relatively new branch of clinical pharmacology focuses on adjusting drug administration times to enhance patient outcomes.

View Article and Find Full Text PDF

Objective/goals: Cognitive decline is intricately linked to various factors such as obesity, stress, poor sleep, and circadian rhythm misalignment, which are interrelated in their impact on cognitive health. Irregular food-intake timing further compounds these issues. The practice of prolonged nightly fasting (PNF) may help synchronize food intake with circadian rhythms, potentially mitigating adverse effects of cognitive decline and associated factors.

View Article and Find Full Text PDF

Postoperative cognitive dysfunction (POCD) is a prevalent clinical issue following anesthesia and surgery. The onset of POCD, which is closely linked to circadian rhythm disturbance in previous studies, yet the underlying mechanism remains elusive. There is increasing evidence showed that mitochondrial architecture is coordinated by the circadian clock which DRP1 playing a crucial role.

View Article and Find Full Text PDF

Biomarkers.

Alzheimers Dement

December 2024

Seoul National University Bundang Hospital, Seongnam, Korea, Republic of (South).

Background: Brain volume is influenced by several factors that can change throughout the day. In addition, most of these factors are influenced by sleep quality. This study investigated diurnal variation in brain volume and its relation to overnight sleep quality.

View Article and Find Full Text PDF

Background: Circadian function, characterized by circadian strength, timing, and fragmentation, has been shown to correlate with cognitive function; however, little is known about in these associations, particularly among older adults who may have more variability in their sleep-wake schedules.

Method: Among 60 community-living adults aged 60-90 years with self-reported sleep complaints ≥once/ week, we investigated gender differences in the associations between circadian and cognitive function. Participants completed seven days of actigraphy and one night of polysomnography.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!