Nine cases of intracranial hemorrhages related to cocaine usage are presented. Another 5 cases from the literature are reviewed. The relationship between severe cocaine-induced hypertension, and the development of subarachnoid or intracerebral hemorrhages is noted, and apparently is related to sudden transient increases of blood pressure related to cocaine use.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/j.1600-0404.1988.tb05891.x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
"Aneurysmal Subarachnoid Hemorrhage and Cocaine Consumption: A Systematic Review and Metanalysis".
World Neurosurg
April 2024
Department of Neurosurgery, All India Institute of Medical Sciences, Bhopal, India.
Article Synopsis
- The study examines the link between cocaine use and poor neurological outcomes in patients with aneurysmal subarachnoid hemorrhage (SAH) through a systematic review and meta-analysis of observational studies.
- Results show that cocaine users experience significantly worse overall outcomes, including higher mortality rates and neurological impairment compared to non-users, although risks for hydrocephalus and seizures were not elevated.
- The findings suggest that cocaine consumption increases the likelihood of vasospasm and other complications in patients suffering from aSAH, highlighting the serious impact of recreational drug use on health.
Imaging of Drug-Related Vasculopathy.
Neuroimaging Clin N Am
February 2024
Department of Radiology, Radiation Oncology and Medical Physics, Box 232, General Campus Room 1466e, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada. Electronic address:
Article Synopsis
- Illicit and recreational drugs like cocaine and heroin, as well as some prescribed medications, can cause vascular issues such as vasculitis or vasculopathy.
- These vascular complications may lead to serious problems in the central nervous system, like strokes and intracranial hemorrhages.
- Imaging techniques such as MR imaging and CT/CTA are important for diagnosing drug-related vascular conditions, and the article explores their causes, symptoms, and imaging results.
Cocaine Use Presenting as Concomitant Myocardial Infraction and Transient Ischemic Attack - A Case Report.
S D Med
April 2023
Avera McKennan Hospital and University Health Center, Sioux Falls, Sioux Falls, South Dakota.
Cocaine abuse with its complications is a common problem that presents often in the emergency room. Complications of cocaine use can involve multiple systems. These complications can arise within each system simultaneously or at different times.
View Article and Find Full Text PDFElevation of Extracellular Glutamate by Blockade of Astrocyte Glutamate Transporters Inhibits Cocaine Reinforcement in Rats via a NMDA-GluN2B Receptor Mechanism.
J Neurosci
March 2022
Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland 21224
It is well established that glutamate plays an important role in drug-induced and cue-induced reinstatement of drug seeking. However, the role of glutamate in drug reward is unclear. In this study, we systemically evaluated the effects of multiple glutamate transporter (GLT) inhibitors on extracellular glutamate and dopamine (DA) in the nucleus accumbens (NAc), intravenous cocaine self-administration, intracranial brain-stimulation reward (BSR), and reinstatement of cocaine seeking in male and female rats.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!