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Effect of epidural analgesia on postoperative opioid requirements following elective laparotomies performed at Vancouver General Hospital. | LitMetric

Effect of epidural analgesia on postoperative opioid requirements following elective laparotomies performed at Vancouver General Hospital.

Am J Surg

Department of Surgery, Faculty of Medicine, University of British Columbia, 2775 Laurel Street, 5th Floor, Vancouver, British Columbia, V5Z 1M9, Canada. Electronic address:

Published: June 2021

Background: Enhanced recovery pathways aim to reduce postoperative opioid use and opioid-related complications. These pathways often include epidural analgesia (EA). This study examines postoperative opioid use after elective laparotomy with and without EA.

Methods: Retrospective chart review of elective laparotomies performed by General Surgery at a tertiary academic center during 2017 was completed. Primary outcome was postoperative opioid usage. Secondary outcomes were time to mobilization, duration of urinary catheterization and postoperative ileus.

Results: Among 236 patients, 213 (90%) received EA. There was no significant difference in mean total oral morphine equivalent (OME) usage between EA and non-EA groups. Mean OME use on postoperative day three was higher in the EA group (38.0 vs 22.4 mg, p = 0.02). On multivariate analysis, preoperative opioid use was associated with increased postoperative OME consumption (regression coefficient 147.5, p < 0.001).

Conclusions: In this cohort, epidural analgesia did not reduce postoperative opioid consumption.

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Source
http://dx.doi.org/10.1016/j.amjsurg.2021.03.025DOI Listing

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