Clinical Conundrum: Neisseria meningitidis Septic Abortion.

J Obstet Gynaecol Can

Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, NS.

Published: April 2021

Septic shock after abortion is an important cause of global maternal mortality but is rarely encountered in developed countries. We describe a case of septic abortion with a novel associated pathogen: Neisseria meningitidis. A 30-year-old multiparous woman presented in septic shock after an incomplete spontaneous abortion. She received empiric antibiotics and vasopressors, underwent an urgent dilatation and curettage, and was admitted to the intensive care unit. Her blood cultures and endometrial tissue were positive for N. meningitidis. Antibiotics were adjusted based on culture, and the patient recovered. Septic shock requires prompt identification, antibiotic administration, and source control. Here, we identify an uncommon pathogen associated with septic abortion and highlight the importance of broad empiric and subsequent culture-guided antibiotic choice to ensure coverage.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jogc.2020.12.006DOI Listing

Publication Analysis

Top Keywords

septic abortion
12
septic shock
12
septic
6
abortion
5
clinical conundrum
4
conundrum neisseria
4
neisseria meningitidis
4
meningitidis septic
4
abortion septic
4
shock abortion
4

Similar Publications

This study reports the diagnosis and treatment of a 26-year-old pregnant woman with severe malnutrition combined with acute pyelonephritis causing sepsis, refractory septic shock and multiple organ failure. A female patient, 26 years old, was admitted to hospital mainly due to "menelipsis for more than 19 weeks, nausea and vomiting for 20 days, fever with fatigue for 3 days". At the end of 19 weeks of intrauterine pregnancy, the patient presented with fever accompanied by urinary tract irritation.

View Article and Find Full Text PDF

The case report examines a rare presentation of tricuspid valve infective endocarditis (TVIE) following a septic abortion. A 31-year-old female presented with persistent high-grade fever, chills, and mild vaginal bleeding post medical termination of pregnancy. Despite initial management for septic abortion, including manual evacuation and antibiotics, her symptoms recurred, necessitating further evaluation.

View Article and Find Full Text PDF
Article Synopsis
  • * A study conducted from June 2021 to December 2023 involved 5 hospitals and found that 10.8% of 5613 women suspected of sepsis had CRKP infections, with high rates of multi-drug resistance (93.9%) and other varying levels of resistance to critical antibiotics.
  • * Risk factors such as septic abortion, extended hospitalization, and cesarean wound infections were significantly associated with developing sepsis, and treatment often included combining carbapenem with other antibiotics for resistant strains.
View Article and Find Full Text PDF

Successful Conservative Management of Second Trimester Spontaneous Abortion Complicated by Clostridial Sepsis.

J Pediatr Adolesc Gynecol

August 2024

Department of Obstetrics and Gynecology, University of Illinois-Chicago, Rockford, IL. Electronic address:

Clostridium perfringens is responsible for 5% of septic abortions. Emergent hysterectomy is often required for patient survival. This can be devastating to patients desiring future fertility.

View Article and Find Full Text PDF
Article Synopsis
  • Uterine clostridial myonecrosis is a rare but deadly infection, highlighted by two cases of maternal mortality linked to Clostridium bacteria during childbirth and medication abortion.
  • The first case involved a 30-year-old woman with septic shock after labor complications, while the second case involved an adolescent who developed septic shock post-abortion, with both patients dying shortly after hospital admission.
  • Timely diagnosis and treatment are critical, requiring quick identification of symptoms and immediate surgical action, such as hysterectomy, along with antibiotics to improve survival chances and prevent fatal outcomes.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!