Aims: This study aimed to estimate the prevalence of the potential drug-herbal interaction among patients with chronic diseases in Al-Kharj, Saudi Arabia and to explore factors associated with the potential of drug-herbal interaction.
Method: A cross-sectional study was conducted through interview-based questionnaire at outpatient clinics in Al-Kharj. The study included patients with chronic diseases who used herbal products.
Results: This study included 336 patients in total. The mean age of participants was 52.4 ± 12.0 years, and their most-used medications were metformin, atorvastatin, and aspirin, while their most-used herbs were ginger (74.7%), mint (72%), and cumin (66.7%). In 310 out of 336 (92.26%) cases, at least one potential drug-herbal interaction was found, and most of these interactions (84%) were moderate.
Conclusion: A substantial percentage of potential drug-herbal interactions were found among patients with chronic diseases. Healthcare providers are encouraged to discuss the safety and efficacy of herbal products with their patients.
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http://dx.doi.org/10.1016/j.ctcp.2021.101324 | DOI Listing |
Cardiovasc Ther
January 2025
Department of Cardiology XuanCheng City Central Hospital, Xuancheng, China.
Modern pharmacological studies have elucidated the presence of aconitine (AC) alkaloids, polysaccharides, and saponins as the primary bioactive constituents of Fuzi. Among these, benzoylaconine, a pivotal active compound, demonstrates notable pharmacological properties including antitumor, anti-inflammatory, and cardiovascular protective effects. In recent years, benzoylaconine has garnered significant attention in basic research on heart diseases, emerging as a focal point of investigation.
View Article and Find Full Text PDFNanomedicine (Lond)
December 2024
Nanotheranostics Drug Discovery Research Group, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Nigeria.
The use of nanoparticles (NPs) in treatment of diseases have increased exponentially recently, giving rise to the science of nanomedicine. The safety of these NPs in humans has also led to the science of nanotoxicology. Due to a dearth of both readily available models and precise bio-dispersion characterization techniques, nanotoxicological research has obviously been constrained.
View Article and Find Full Text PDFCureus
October 2024
Health Informatics, University of Hail College of Public Health and Health Informatics, Hail, SAU.
Background The use of herbal remedies is prevalent in Hail, Kingdom of Saudi Arabia, but the concurrent use of pharmaceutical drugs poses significant risks due to potential drug-herbal interactions. Understanding public awareness and perceptions of these interactions is crucial for enhancing public health education and safety. This study aimed to (1) assess the prevalence of herbal medicine use among the Hail population, (2) evaluate awareness and knowledge regarding drug-herbal interactions, and (3) identify common sources of information about these interactions.
View Article and Find Full Text PDFJ Ethnopharmacol
February 2025
Jilin Provincial Key Laboratory for Molecular and Chemical Genetics, The Second Hospital of Jilin University, Changchun, 130041, PR China; Engineering Laboratory for Screening of Antidepressant Drugs, Jilin Province Development and Reform Commission, Changchun, 130041, PR China; Jilin Provincial Key Laboratory on Target of Traditional Chinese Medicine with Anti-depressive Effect, Changchun, 130041, PR China. Electronic address:
Ethnopharmacological Relevance: Fuzi-Lizhong pill (FLP) is a well-validated traditional Chinese medicine (TCM) formula that has long been used in China for gastrointestinal disease and adjunctive therapy for depression. In our previous study, we reported that the principal herb of FLP, Aconitum carmichaelii Debx. (Fuzi), exhibits antidepressant-like effects.
View Article and Find Full Text PDFPer Med
December 2024
Centre for Drug & Herbal Development, Faculty of Pharmacy, Universiti Kebangsaan Malaysia, Kuala Lumpur, 50300, Malaysia.
Rs16851030, a single-nucleotide variant located in the 3'-untranslated region of the gene, has been proposed as a potential marker of caffeine sensitivity in apnea of prematurity. Besides, it is associated with aspirin-induced asthma and the development of acute chest syndrome. However, its functional significance is still unconfirmed.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!