Two polypropylene HVAC electret filters: a regular filter and an antimicrobial filter containing zinc pyrithione (ZPT), were compared for filtration performance. The study was conducted over 7 months in realistic conditions with semi-urban outdoor air. Several parameters were monitored over the study period: the average temperature was about 20 °C and relative humidity about 60%, the average inlet concentration of cultivable microorganisms was 50 CFU m, the average inlet concentration of particles was 10 μg m, the filter pressure drop increased moderately by about 30 Pa, and the particle collection efficiency of soda fluorescein (median diameter 0.35 μm) decreased in the first half of the study period by about 30% and then stabilized. The microbial concentration on the filters was quantified every 2 months using an innovative methodology based on media coupons in conjunction with microorganism quantification by CFU counting, with 5 culture media favorable to bacteria and/or fungi growth. The microbial concentrations on the filters were between 100 and 2000 CFU cm. The antimicrobial effect of zinc pyrithione was confirmed by the fungi cultivated with DRBC agar: no effects in the level of filter clogging were revealed in the range studied. The high statistical deviation in the results regarding the inhibiting effect of zinc pyrithione on bacteria prevents any conclusion.
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http://dx.doi.org/10.1007/s11356-021-13330-w | DOI Listing |
Int J Cosmet Sci
January 2025
Unilever Research and Development Port Sunlight Laboratory, Wirral, UK.
Objective: Dandruff is a common scalp condition characterized by the chronic shedding of large clumps of epidermal cells. Alongside negative physical symptoms, dandruff is thought to have a detrimental impact on individuals' mental health. The aim of this study was to determine whether the clinical benefits of using an anti-dandruff shampoo (ADS) will result in improved psychological wellbeing in individuals suffering from dandruff.
View Article and Find Full Text PDFOncogene
January 2025
State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, China.
Mismatch repair deficiency (dMMR) cancers are highly sensitive to immunotherapy, but only account for a small fraction of cancer patients. How to increase immunotherapy efficacy on MMR-proficient (pMMR) cancer is still a major challenge. This study demonstrates that pyrithione zinc (PYZ), an FDA-approved drug, can enhance tumor immunogenicity via altering MMR and activating STING signaling.
View Article and Find Full Text PDFJ Cosmet Dermatol
January 2025
Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Background: The occurrence of scalp seborrheic dermatitis (SD) is closely related to the production of sebum and scalp barrier function. Supramolecular salicylic acid has the keratolytic and anti-inflammatory properties, and zinc pyrithione is an antifungal drug delivered as a microparticle to skin epithelia.
Objective: This study aimed to assess the efficacy and safety of 2% supramolecular salicylic acid (SSA) combined with 0.
Cureus
September 2024
Savlon Swasth India Mission, ITC Life Sciences and Technology Centre, Bangalore, IND.
Background: Seborrheic dermatitis is a common scalp condition affecting the quality of life of individuals across all age groups. The uninhibited proliferation of and enhanced sebaceous gland activity often leads to scalp flaking, mild erythema, and itching, thereby worsening the situation. Here, we aimed to study the efficacy of an antiseptic liquid as a pre-shampoo rinse followed by a non-anti-dandruff shampoo as a dandruff care strategy.
View Article and Find Full Text PDFLife Sci
December 2024
Department of Pharmacology, School of Pharmacy, Qingdao University Medical College, #1 Ningde Road, Qingdao 266073, China. Electronic address:
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