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The differential diagnoses of inflammatory hip diseases play an important role for the diagnosis of hip pain. The radiological manifestations of rheumatic inflammatory hip pain with the corresponding use of imaging modalities were dealt in part 1 of the CME article. In this second part a systematic approach is explained in order to differentiate the many rheumatic diseaeses from degeneration, synovial tumors and infections. The interpretation of the pathologies seen in imaging in association with the clinical phenotype is more precisely elucidated for the individual differential diagnoses. The concomitant occurrence of different diseases, sometimes as secondary complications, has a substantial influence on treatment planning and should be recognized by radiologists.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8012330 | PMC |
http://dx.doi.org/10.1007/s00117-021-00835-1 | DOI Listing |
J Arthroplasty
March 2025
McMaster University, Department of Surgery, Division of Orthopaedic Surgery, Hamilton, ON, Canada.
Background: Hip and knee arthroplasty are a fundamental part of modern orthopaedic practice. These procedures often require extensive postoperative analgesia, including opiate painkillers that are frequently associated with adverse side effects and risk of abuse. This review, therefore, investigated how postoperative administration of non-opioid co-analgesics (e.
View Article and Find Full Text PDFBMC Rheumatol
March 2025
Musculoskeletal Innovative Research Lab (mskil), University of Liège, Liège, Belgium.
Objectives: Osteoarthritis (OA), a prevalent and disabling condition, significantly burdens individuals and healthcare systems worldwide. It is characterized by joint pain, stiffness, and structural changes in cartilage, bone, and synovium. The clinical manifestations of OA vary widely, reflecting complex interactions among genetic, metabolic, biomechanical, and environmental factors.
View Article and Find Full Text PDFBMC Musculoskelet Disord
March 2025
Department of Anesthesiology, Jiangdu People's Hospital Affiliated to Yangzhou University, No. 100, Jiangzhou Road, Jiangdu District, Yangzhou, 225200, China.
Background: The duration of a single fascia iliaca compartment block (FICB) with ropivacaine is limited. This study investigated whether methylene blue as an adjuvant anesthetic in FICB can enhance the postoperative analgesic effect following total hip arthroplasty (THA).
Methods: Patients who planned to undergo THA were recruited for this randomized clinical trial from June 2023 to February 2024.
Mamm Genome
March 2025
Department of Neurosurgery, Xiangya Hospital, Central South University, Changsha, China.
The causal relationships between neuroticism and osteoarthritis (OA) were inconclusive in observational studies. We conducted bidirectional two-sample Mendelian randomization (MR) and transcriptome-wide association studies to determine the associations and the underlying transcriptomic basis. The summary-level genome-wide association study data for any site OA, knee OA, erosive hand OA, and hip OA were mainly derived from UK Biobank, and neuroticism was derived from CTGlab.
View Article and Find Full Text PDFPurpose: Evolving evidence demonstrates the role of epigenetics in the pathogenesis of osteoarthritis (OA), whereas in terms of mechanism, DNA methylation has received the highest attention thus far. This systematic review summarizes the current knowledge of DNA methylation and its influence on the pathogenesis of OA.
Methods: A protocol in alignment with the PRISMA guidelines was employed to systematically review eight bibliographic databases between 1 January 2015 and 31 January 2021, to identify associations between DNA methylation and articular chondrocytes in OA.
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