Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/rheumatology/keab281 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antiviral therapy for hepatitis B virus infection is beneficial for the prognosis hepatocellular carcinoma.
World J Gastrointest Oncol
January 2025
Institute of Liver Diseases, Institute of Translational Medicine, The First Hospital of Jilin University, Changchun 130061, Jilin Province, China.
In this editorial, we comment on the article by Mu , published in the recent issue of the . We pay special attention to the immune tolerance mechanism caused by hepatitis B virus (HBV) infection, the pathogenesis of hepatocellular carcinoma (HCC), and the role of antiviral therapy in treating HCC related to HBV infection. HBV infection leads to systemic innate immune tolerance by directly inhibiting pattern recognition receptor recognition and antiviral signaling pathways, as well as by inhibiting the immune functions of macrophages, natural killer cells and dendritic cells.
View Article and Find Full Text PDFRegulatory networks may evolve to favor adaptive foresight.
PLoS Biol
December 2024
Centro de Biotecnología y Genómica de Plantas (CBGP), Universidad Politécnica de Madrid (UPM), Madrid, Spain.
Pleiotropy-a single mutation altering many traits-has long been seen as hindering adaptation. A new study in PLOS Biology offers a striking counterexample, suggesting that regulatory networks may evolve to ensure mutations are simultaneously beneficial in correlated environments.
View Article and Find Full Text PDFIs 26S proteasome non-ATPase regulatory subunit 6 a potential molecular target for intrahepatic cholangiocarcinoma?
World J Hepatol
November 2024
Hepatosplenic Surgery Center, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.
Article Synopsis
- The article discusses the challenges of treating intrahepatic cholangiocarcinoma (iCCA), as most patients do not respond well to existing therapies and highlights ongoing efforts to find new molecular targets.
- It focuses on a study by Tang which examines the role of the PSMD6 gene in iCCA cells, finding it crucial for cell proliferation and overexpressed in iCCA tissues, although the study has limitations regarding its methods and insights into mechanisms.
- The editorial also mentions recent advancements in targeted drug therapies and immunotherapies for iCCA, and underscores the potential of CRISPR technology and other computational methods in cancer research.
Differential diagnosis of gastric submucosal masses and external pressure lesions.
World J Gastrointest Surg
October 2024
Department of General Surgery, Weifang People's Hospital, Weifang 261041, Shandong Province, China.
Lesions of the left triangular ligament of the liver are rare, and there are even fewer cases of vascular tumors misdiagnosed as gastrointestinal stromal tumors. We comment on the two cases reported in the article. The article did not include pictures of laparoscopic surgery, making it unconvincing.
View Article and Find Full Text PDFIs fruits granola beneficial for blood pressure management?
Hypertens Res
January 2025
Department of Pharmacology, Faculty of Medicine, Kagawa University, 7610793, Kagawa, Japan.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!