AI Article Synopsis
- The study aimed to estimate COVID-19-related mortality in Los Angeles County by calculating excess all-cause and pneumonia, influenza, or COVID (PIC) deaths from March to August 2020.
- Researchers analyzed vital statistics data, calculating expected deaths and comparing them to actual deaths to determine excess mortality, while also classifying deaths based on COVID-19 test results.
- Findings revealed 7,208 excess all-cause deaths and 5,128 excess PIC deaths, closely matching the 5,160 confirmed and 323 probable COVID-19 deaths reported, indicating the surveillance method used may effectively capture COVID-19 mortality rates.
Article Abstract
Objective: To more comprehensively estimate COVID-19-related mortality in Los Angeles County by determining excess all-cause mortality and pneumonia, influenza, or COVID (PIC) mortality.
Design: We reviewed vital statistics data to identify deaths registered in Los Angeles County between March 15, 2020, and August 15, 2020. Deaths with an ICD-10 (International Classification of Diseases, Tenth Revision) code for pneumonia, influenza, or COVID-19 listed as an immediate or underlying cause of death were classified as PIC deaths. Expected deaths were calculated using negative binomial regression. Excess mortality was determined by subtracting the expected from the observed number of weekly deaths. The Department of Public Health conducts surveillance for COVID-19-associated deaths: persons who died of nontraumatic/nonaccidental causes within 60 days of a positive COVID-19 test result were classified as confirmed COVID-19 deaths. Deaths without a reported positive SARS-Cov-2 polymerase chain reaction result were classified as probable COVID-19 deaths if COVID-19 was listed on their death certificate or the death occurred 60 to 90 days of a positive test. We compared excess PIC deaths with the number of confirmed and probable COVID-19 deaths ascertained by surveillance.
Setting: Los Angeles County.
Participants: Residents of Los Angeles County who died.
Main Outcome Measure: Excess mortality.
Results: There were 7208 excess all-cause and 5128 excess PIC deaths during the study period. The Department of Public Health also reported 5160 confirmed and 323 probable COVID-19-associated deaths.
Conclusions: The number of excess PIC deaths estimated by our model was approximately equal to the number of confirmed and probable COVID-19 deaths identified by surveillance. This suggests our surveillance definition for confirmed and probable COVID-19 deaths might be sufficiently sensitive for capturing the true burden of deaths caused directly or indirectly by COVID-19.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/PHH.0000000000001344 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Trends in sepsis-associated cardiovascular disease mortality in the United States, 1999 to 2022.
Front Cardiovasc Med
December 2024
Department of Cardiology, Creighton University Medical Center, Omaha, NE, United States.
Purpose: Cardiovascular disease (CVD) is the leading cause of death in the United States, and sepsis significantly contributes to hospitalization and mortality. This study aims to assess the trends of sepsis-associated CVD mortality rates and variations in mortality based on demographics and regions in the US.
Methods: The Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) database was used to identify CVD and sepsis-related deaths from 1999 to 2022.
Cardiovascular Complications in Children Post COVID-19: A Systematic Review.
Adv Biomed Res
October 2024
Department of Pediatrics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Cardiovascular involvements are one of the most important and threatening problems of SARS-CoV-2 infection and can cause a wide range of clinical manifestations in children. Therefore, a review of previous studies is necessary to prevent the occurrence of cardiovascular complications and reduce the risk of mortality in this age group of patients. To investigate the cardiovascular complications in children with COVID-19, international authoritative databases including PubMed, Scopus, Embase, Web of Science, Google Scholar, and Persian databases were searched using the main concepts, all articles were published between January 2020 and November 2022.
View Article and Find Full Text PDFUnderstanding Post-COVID-19: Mechanisms, Neurological Complications, Current Treatments, and Emerging Therapies.
Int J Gen Med
December 2024
Department of Health Sciences, Universidad San Francisco de Quito USFQ, School of Medicine, Quito, Ecuador.
COVID-19, a highly infectious disease, caused a worldwide pandemic in early 2020. According to the World Health Organization (WHO), COVID-19 has resulted in approximately 774 million cases and around 7 million deaths. The effects of COVID-19 are well known; however, there is a lack of information on the pathophysiological mechanisms underlying the symptoms that comprise Post-Acute COVID-19 Syndrome (PACS) or Long COVID-19.
View Article and Find Full Text PDFEpidemiological Characteristics and Outcome of Myocarditis and Pericarditis Temporally Associated With BNT162b2 COVID-19 Vaccine in Adolescents: Korean National Surveillance.
J Korean Med Sci
December 2024
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Background: This study aimed to investigate the epidemiological characteristics and outcomes of myocarditis/pericarditis after BNT162b2 vaccination in Korean adolescents.
Methods: This was a retrospective cohort analysis of adolescents aged 12-19 years old diagnosed with myocarditis/pericarditis within 42 days of BNT162b2 mRNA vaccination. All reported cases were investigated by city or government epidemiologists and the diagnostic certainty and causality was determined by the Korea Disease Control and Prevention Agency's Adverse Event Following Immunization Expert Advisory Committee according to the modified version of Brighton Collaboration Myocarditis/Pericarditis Working group's case definitions.
The Application of Different Pulmonary Ultrasound Scores in Severe Pneumonia Patients.
Curr Med Imaging
December 2024
Department of Ultrasound, The Affiliated Hospital, Southwest Medical University, 319 Zhongshan Road, LuZhou 646000, Sichuan, P.R. China.
Severe pneumonia (SP) is a common cause of septic shock and Acute Respiratory Distress Syndrome (ARDS), leading to multiorgan dysfunction syndrome. Patients with SP often require respiratory support, and SP is associated with high mortality and is a significant economic burden for hospitalized patients. Therefore, early identification and real-time monitoring of the severity of SP are crucial for improving outcomes.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!