AI Article Synopsis
- This meta-analysis investigates the risk factors for acute kidney injury (AKI) in adults undergoing extracorporeal membrane oxygenation (ECMO), identifying a lack of systematic studies on this issue.
- Authors conducted a thorough literature review from multiple databases to analyze data from 12 relevant studies, focusing on various clinical factors such as age, gender, and specific health conditions.
- Findings indicate that older patients and those with higher APACHE II and SOFA scores, as well as diabetes and prolonged ECMO duration, are more likely to experience severe AKI, highlighting the need for increased monitoring for these patients during ECMO treatment.
Article Abstract
Purpose: Acute kidney injury (AKI) is one of the most common complications in patients receiving extracorporeal membrane oxygenation (ECMO), but there is no systematic analysis regarding its risk factors. This meta-analysis aims to determine the risk factors of AKI in adult patients with ECMO treatment.
Methods: Two authors independently carried out a systemic literature search using PubMed, Web of Science, and Embase until April 20, 2020 (inclusive) to enroll 12 studies reporting the necessary clinical characteristics. The Gender (male), age, APACHE II score, SOFA score, cancer, diabetes mellitus (DM), intra-aortic balloon pump (IABP), postcardiotomy, and ECMO supporting duration were pooled for further analysis by STATA.
Results: Adult patients receiving ECMO who develop AKI and severe AKI incidents are usually older or have a higher APACHE II scores; in addition, severe AKI is related to higher SOFA scores, DM, and longer duration of ECMO support.
Conclusions: Patients with these clinical characteristics should be paid more attention during ECMO. There remains a need for additional studies to validate these conclusions and to detect additional AKI risk factors for ECMO patients.
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| http://dx.doi.org/10.1177/08850666211003485 | DOI Listing |
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