Does insulin resistance trigger thyroid nodule?

Intern Emerg Med

Internal Medicine, Tepecik Training and Research Hospital, University of Health Sciences, Izmir, Turkey.

Published: November 2021

AI Article Synopsis

  • - The study explores the unclear relationship between insulin resistance and thyroid nodules in non-diabetic patients, analyzing data from 410 patients at an Internal Medicine outpatient clinic.
  • - Out of the reviewed patients, 216 were non-diabetic and were divided into two groups: 105 had thyroid nodules and 110 did not, with findings indicating a higher insulin resistance measurement and greater cholesterol and triglyceride levels in the nodule group.
  • - A significant positive correlation was found between insulin resistance and the presence of thyroid nodules, suggesting that insulin resistance could be linked to nodule formation, although further research is needed to confirm these results.

Article Abstract

The relationship between insulin resistance and thyroid nodules is not clearly understood. The purpose of this study is to investigate the relationship between insülin resistance and thyroid nodules in non-diabetic patients. 410 patients who applied to the Internal Medicine outpatient clinic from June 2018 to July 2019 were reviewed retrospectively. A total of 216 non-diabetic patients were divided into two groups. The relationship of 105 patients with thyroid nodules and 110 patients without thyroid nodules with insulin resistance was investigated. Homeostasis model assessment of insulin resistance value, serum triglycerides and total cholesterol level, and the ratio of women were higher in the group with thyroid nodules (p < 0.05). There was a positive and significant relationship between homeostasis model assessment of insulin resistance value and thyroid nodules (r + 0.29, p < 0.05). In non-diabetic thyroid nodule patients, a significant relationship was detected between nodule formation and insulin resistance. However, these data must be confirmed by other studies in the future.

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Source
http://dx.doi.org/10.1007/s11739-021-02713-zDOI Listing

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