In a recent paper [Chaos 30, 073139 (2020)], we analyzed an extension of the Winfree model with nonlinear interactions. The nonlinear coupling function Q was mistakenly identified with the non-infinitesimal phase-response curve (PRC). Here, we assess to what extent Q and the actual PRC differ in practice. By means of numerical simulations, we compute the PRCs corresponding to the Q functions previously considered. The results confirm a qualitative similarity between the PRC and the coupling function Q in all cases.
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The organizational principles of nephronal segments are based on longstanding anatomical and physiological attributes that are closely linked to the homeostatic functions of the kidney. Novel molecular approaches have recently uncovered layers of deeper signatures and states in tubular cells that arise at various timepoints on the spectrum between health and disease. For example, a dedifferentiated state of proximal tubular cells with mesenchymal stemness markers is frequently seen after injury.
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January 2025
Department of Ecology, Evolution and Natural Resources, Rutgers University, New Brunswick, New Jersey, USA.
Substantial evidence suggests that biodiversity can stabilize ecosystem function, but how it does this is less clear. In very general terms, the hypothesis is that biodiversity stabilizes function because having more species increases the role of compensatory dynamics, which occur when species in a community show different responses to the environment. Here, we focus on two forms of compensatory dynamics, cross-scale redundancy (CSR) and response diversity (RD).
View Article and Find Full Text PDFAm J Physiol Renal Physiol
November 2024
Division of Nephrology, Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States.
Med Phys
September 2024
Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA.
Background: Inserting noise into existing patient projection data to simulate lower-radiation-dose exams has been frequently used in traditional energy-integrating-detector (EID)-CT to optimize radiation dose in clinical protocols and to generate paired images for training deep-learning-based reconstruction and noise reduction methods. Recent introduction of photon counting detector CT (PCD-CT) also requires such a method to accomplish these tasks. However, clinical PCD-CT scanners often restrict the users access to the raw count data, exporting only the preprocessed, log-normalized sinogram.
View Article and Find Full Text PDFTrends Ecol Evol
May 2024
Argentine Institute for Dryland Research, National Council for Scientific and Technical Research (CONICET)-National University of Cuyo, Mendoza 5500, Argentina; Faculty of Exact and Natural Sciences, National University of Cuyo, Mendoza M5502, Argentina. Electronic address:
Plant-pollinator interactions are ecologically and economically important, and, as a result, their prediction is a crucial theoretical and applied goal for ecologists. Although various analytical methods are available, we still have a limited ability to predict plant-pollinator interactions. The predictive ability of different plant-pollinator interaction models depends on the specific definitions used to conceptualize and quantify species attributes (e.
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