The orbital myositis is a rare inflammatory disorder of extraocular muscles and is considered a subtype of nonspecific orbital inflammatory syndrome. It is usually a unilateral disease process with a limited course. We report a case of a 34-year-old man who was referred to the Radiology Department at Shifa International Hospital, Islamabad with 6 months history of severe pain, swelling, and redness in the left eye associated with blurring of vision and headache. Initially, the patient had contrast enhanced CT scan orbits which showed asymmetrically thickened, minimally enhancing left optic nerve having indistinct margins with thickened superior rectus and superior oblique muscles, indistinct superior ophthalmic vein, soft tissue nodularity in the medial intraconal space fat, and slight left exophthalmos. Differentials of orbital pseudo tumour and lymphoma were given. Further evaluation by post contrast MRI with orbits protocol was suggested which showed proptosis, the significant infiltrative disease in the superomedial aspect of left orbit involving the adjacent fat with thickening, enlargement, and heterogeneous enhancement of the superior rectus, medial rectus, and superior oblique muscles with relatively lesser degree involvement of their tendons. The infiltrative thickening also involved the optic nerve sheath and seen invading the optic nerve at the orbital apex. On basis of the imaging features and clinical picture, a diagnosis of orbital myositis with optic neuropathy was given. The patient was given corticosteroids and showed rapid symptomatic improvement.
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Int J Rheum Dis
January 2025
Department of Internal Medicine, Hedi Chaker University Hospital, Sfax, Tunisia.
Zhonghua Yan Ke Za Zhi
January 2025
Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Ophthalmology, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing100730, China.
Immune checkpoint inhibitors (ICI), as a new type of targeted therapeutic drugs, have demonstrated durable efficacy in cancer treatment. However, some patients receiving ICI treatment may be affected by immune-related adverse events (irAE). Compared with irAE in skin tissues, gastrointestinal system, etc.
View Article and Find Full Text PDFArch Soc Esp Oftalmol (Engl Ed)
December 2024
Servicio Oftalmología, Hospital Alfredo Espinosa, Urduliz, Bizkaia, Spain.
A 66-year-old woman presents with unilateral orbital inflammation of several years of evolution, initially classified as idiopathic orbital inflammatory disease (IOID) subtype myositis. She presented with pain, eyelid inflammation and significant elevation of intraocular pressure, as well as radiological signs of exophthalmos and superior rectus myositis. She was treated with corticosteroids, with partial response.
View Article and Find Full Text PDFNeurology
January 2025
From the Department of Neurology, Huashan Hospital, Fudan University, Shanghai, China.
Balkan Med J
January 2025
Department of Internal Medicine, Tokyo Metropolitan Matsuzawa Hospital, Setagaya, Tokyo, Japan
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