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Pharmaceutical interviews to overcome digestive artefacts on [ Tc]Tc-tetrofosmin myocardial perfusion scintigraphy. | LitMetric
What Is Known And Objectives : Poor image quality was randomly seen in [ Tc]Tc-tetrofosmin myocardial perfusion scintigraphic imaging. The interference hampered or even precluded medical interpretation. Our objective was to identify the cause of the random interferences.Methods : Out of 40 patients planned for [ Tc]Tc-tetrofosmin MPS, 36 presented normal tracer uptake and 4 exhibited subdiaphragmatic artefacts. Pharmaceutical interviews (P.I.) were set up to formally identify aetiologies of subdiaphragmatic uptake of [ Tc]Tc-tetrofosmin. Patients were questioned about their diet and current drug treatments.Results And Discussion : P.I. led to identification of dipyridamole as the cause of the artefacts. The systematic ingestion of a solid 25-gram high-fat snack bar and a glass of fresh water was introduced immediately after the injection of dipyridamole in 12 other patients undergoing [ Tc]Tc-tetrofosmin MPS. None of the 12 patients presented subdiaphragmatic artefacts.What Is New And Conclusion : P.I. identified the cause of poor scintigraphic images to allow improved diagnoses.
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