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Risk of residual/recurrent cervical diseases in HPV-positive women post-conization depends on HPV integration status.
Infect Agent Cancer
January 2025
College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, Fujian, 350001, China.
Background: It is crucial to identify post-operative patients with HPV infection who are at high risk for residual/recurrent disease. This study aimed to evaluate the association between HPV integration and clinical outcomes in HPV-positive women after cervical conization, as well as to identify HPV integration breakpoints.
Methods: This retrospective study analyzed data of 791 women who underwent cervical conization for cervical intraepithelial neoplasia grades 2-3 (CIN2-3) between September 2019 and September 2023, sourced from the Fujian and Hubei cervical lesion screening cohorts.
Seeking consensus on dilemmas related to euthanasia in dementia based on an advance directive: a Delphi study from a medical, ethical and legal perspective.
J Med Ethics
January 2025
Medicine for Older People, AmsterdamUMC Location VUmc, Amsterdam, The Netherlands.
Euthanasia in dementia based on advance euthanasia directives (AEDs) is possible within the Dutch Euthanasia law. Yet, physicians struggle with the responsibility of interpreting the law's open norms in cases of advanced dementia, which includes the fulfilment of the due care criteria. This Delphi study aims to analyse arguments and seek consensus from medical, ethical and legal perspectives on ethical dilemmas in such cases.
View Article and Find Full Text PDFTemporary Global Amnesia With Insular Infarction in a Young Female: A Case Report.
Cureus
December 2024
Division of Internal Medicine, Miyagi Central Hospital, Sendai, JPN.
Several neurological conditions, including transient global amnesia (TGA), may present an isolated sudden-onset temporary amnestic symptom. TGA is a benign, self-remitting neurological condition associated with hippocampal dysfunction. Meanwhile, certain other neurological conditions, such as cerebral ischemic stroke and hippocampal epilepsy, require appropriate therapeutic interventions.
View Article and Find Full Text PDFOn-farm diversity and production challenges in Ethiopian tef [ ((Zuccagni) Trotter)] landraces from Arsi zone, Ethiopia: Implications for breeding and conservation.
Heliyon
January 2025
Madda Walabu University, College of Agriculture, Forestry Department, P.O.Box 247, Bale Robe, Ethiopia.
Context: Tef [ ((Zucc.) Trotter)] is a remarkable indigenous crop, highly adaptive and resilient to erratic and extreme climatic and soil conditions. It is a major staple food in Ethiopia and is usually cultivated for household consumption and the generation of income.
View Article and Find Full Text PDFVV-ECMO adjuvant therapy for complicated with H1N1 infection: a case report.
Front Med (Lausanne)
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Department of Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Guangxi Clinical Research Center for Critical Care Medicine, Guangxi, China.
Background: Leptospirosis is an acute infectious disease that occurs by infection, progresses rapidly, and has a high mortality rate, with an estimated 1.2 million new cases and nearly 59,000 deaths each year. Due to its diverse clinical manifestations, diagnosis is often delayed.
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