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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906510 | PMC |
| http://dx.doi.org/10.1016/j.ejim.2021.02.016 | DOI Listing |
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Article Synopsis
- The Wellcome Trust Case Control Consortium 3 conducted a genome-wide association scan for anorexia nervosa using 2,907 cases from 15 European populations and the Illumina 670K chip.
- The study compared different methods to identify population stratification, suggesting that using all SNPs with a minor allele frequency (MAF) greater than 1% could be more effective than the usual threshold of 5%.
- Principal component analysis revealed significant genetic variation across the populations, helping to identify hidden stratification and offering insights for better designing and interpreting association studies in international research efforts.
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