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| http://dx.doi.org/10.1186/s13054-021-03531-7 | DOI Listing |
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The COSMOS Registry of CytoSorb Hemoadsorption Therapy in Critically Ill Patients: Protocol for an International, Prospective Registry.
JMIR Res Protoc
November 2024
Intensive Care Department, Vall d'Hebron University Hospital, Shock, Organ Dysfunction and Resuscitation Research Group (SODIR), Barcelona, Spain.
Background: Extracorporeal blood purification with CytoSorb has been increasingly used as an adjunctive therapy in several hyperinflammatory critical care conditions, as well as to remove elevated levels of myoglobin or bilirubin in patients with rhabdomyolysis or liver failure. Despite the increasing worldwide use of hemoadsorption, data from large international multicenter studies are still lacking.
Objective: The COSMOS (CytoSorb Treatment Of Critically Ill Patients) registry is a company-sponsored registry by CytoSorbents Corporation and CytoSorbents Medical Inc.
[Effect of Plasmafiltration and Adsorption in Cocaine Abuse: A Case Report].
G Ital Nefrol
August 2024
UOC Nefrologia e Dialisi, PO Di Venere, Bari.
Article Synopsis
- * The condition arises from changes in blood flow, direct muscle damage, or immune responses, with treatment options including supportive care and potential apheresis therapy, still needing more validation.
- * A case study of a 52-year-old man with severe complications from cocaine use showed that selective apheresis combined with hemodialysis significantly improved his kidney function and blood parameters after two treatment sessions.
A retrospective analysis of clinical characteristics and outcomes of pediatric fulminant myocarditis.
BMC Pediatr
August 2024
Nanjing Medical University Affiliated Nanjing Children's Hospital, Nanjing, 210008, China.
Background: The study aimed to explore clinical indicators that can predict the prognosis of children with acute fulminant myocarditis (AFM) through a retrospective analysis.
Methods: A retrospective analysis was conducted on the clinical indices of 79 children diagnosed with AFM and hospitalized from March 2013 to March 2023. Relevant demographic and clinical data, including symptoms at admission, laboratory results, and outcomes were extracted to identify factors associated with in-hospital mortality.
Hemoadsorption therapy for myoglobin removal in rhabdomyolysis: consensus of the hemoadsorption in rhabdomyolysis task force.
BMC Nephrol
July 2024
Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, D-48149, Münster, Germany.
Background: Rhabdomyolysis describes a syndrome characterized by muscle necrosis and the subsequent release of creatine kinase and myoglobin into the circulation. Myoglobin elimination with extracorporeal hemoadsorption has been shown to effectively remove myoglobin from the circulation. Our aim was to provide best practice consensus statements developed by the Hemoadsorption in Rhabdomyolysis Task Force (HRTF) regarding the use of hemadsorption for myoglobin elimination.
View Article and Find Full Text PDFMyoglobin adsorption and saturation kinetics of the cytokine adsorber Cytosorb® in patients with severe rhabdomyolysis: a prospective trial.
Ann Intensive Care
June 2024
Department of Anaesthesiology, LMU University Hospital, LMU Munich, Munich, Germany.
Background: Rhabdomyolysis is a serious condition that can lead to acute kidney injury with the need of renal replacement therapy (RRT). The cytokine adsorber Cytosorb® (CS) can be used for extracorporeal myoglobin elimination in patients with rhabdomyolysis. However, data on adsorption capacity and saturation kinetics are still missing.
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