Objective: Alcohol intake is a known risk factor for breast cancer. National organizations recommend that women consume no more than one serving of alcohol per day, if at all; however, many women exceed this recommendation, and some are unwilling to decrease consumption. Our study sought to identify factors associated with women's unwillingness to decrease their alcohol intake to decrease their breast cancer risk.
Methods: 942 women in a screening mammography cohort were asked questions about their demographics, personal and family health history, lifestyle factors, and willingness/unwillingness to decrease alcohol intake to decrease their breast cancer risk. Univariate and multivariate analyzes of their responses were performed.
Results: 13.2% of women in our cohort indicated they were unwilling to decrease their alcohol intake to reduce their breast cancer risk. After adjusting for potential confounders, women who were 60 years and older were more than twice as unwilling to decrease their alcohol intake compared to their younger counterparts ( = .0002). Women who had an annual household income of more than $200,000 were 1.75 times more unwilling to decrease their alcohol intake compared to their less affluent counterparts ( = .033). Unwillingness was not significantly associated with race/ethnicity, education, having a first-degree family member with cancer, health perception, breast cancer risk perception, or BMI.
Conclusions: Levels of unwillingness to decrease alcohol intake differed by age and household income. An opportunity is present to potentially decrease breast cancer risk in the community by educating women, especially older and more affluent women, about alcohol as a risk factor for breast cancer and the importance of limiting one's alcohol intake.
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http://dx.doi.org/10.1177/21501327211000211 | DOI Listing |
J Orthop Surg Res
January 2025
Department of Joint Osteopathy, Liuzhou Worker's Hospital, Liuzhou, Guangxi Province, 545000, China.
Alcoholic osteonecrosis of the femoral head (AIONFH) is caused by long-term heavy drinking, which leads to abnormal alcohol and lipid metabolism, resulting in femoral head tissue damage, and then pathological necrosis of femoral head tissue. If not treated in time in clinical practice, it will seriously affect the quality of life of patients and even require hip replacement to treat alcoholic femoral head necrosis. This study will confirm whether M2 macrophage exosome (M2-Exo) miR-122 mediates alcohol-induced BMSCs osteogenic differentiation, ultimately leading to the inhibition of femoral head necrosis.
View Article and Find Full Text PDFClin Nutr ESPEN
January 2025
Section of Preventive Medicine and Epidemiology, Department of Medicine, Chobanian and Avedisian School of Medicine, Boston University; Department of Health Sciences, Sargent College of Health and Rehabilitation Sciences, Boston University. Electronic address:
Background And Aims: The prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease has increased in parallel with a rise in consumption of ultra-processed foods (UPF), but little is known about their association.
Methods: We cross-sectionally examined associations of UPF with hepatic steatosis and fibrosis in 2,458 (mean age 54 years; 55.9% women) community-dwelling adults who completed vibration-controlled transient elastography and a food frequency questionnaire.
Alcohol
January 2025
Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA; Center for Genetic Epidemiology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Excessive alcohol consumption is a significant public health concern and contributes to liver diseases and cancer. Modifiable lifestyle factors including alcohol consumption can influence circulating microRNAs (miRNAs), which are increasingly used as biomarkers for early disease detection. Yet limited studies have identified miRNAs associated with alcohol intake, particularly in multiethnic populations.
View Article and Find Full Text PDFCien Saude Colet
January 2025
Universidade Federal do Espírito Santo. Vitória ES Brasil.
The scope of this article is to analyze the correlation between alcohol consumption and abdominal obesity in participants of the ELSA-Brasil cohort after a follow-up period of nine years. A longitudinal analysis was performed with baseline and follow-up data from ELSA-Brasil. At baseline, 15,105 civil servants were enrolled.
View Article and Find Full Text PDFAlcohol Clin Exp Res (Hoboken)
January 2025
Department of Psychiatry & Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA.
Background: While alcohol has been shown to impair eye movements in young adults, little is known about alcohol-induced oculomotor impairment in older adults with longer histories of alcohol use. Here, we examined whether older adults with chronic alcohol use disorder (AUD) exhibit more acute tolerance than age-matched light drinkers (LD), evidenced by less alcohol-induced oculomotor impairment and perceived impairment.
Method: Two random-order, double-blinded laboratory sessions with administration of alcohol (0.
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