AI Article Synopsis
- The study aimed to evaluate the risk of coronavirus transmission to healthcare workers during aerosol-generating procedures and assess the effectiveness of personal protective equipment (PPE) in mitigating this risk.
- A systematic search of medical databases identified 17 studies relevant to the transmission of coronaviruses in anesthesia and critical care settings, which were used for meta-analysis.
- Key findings indicated that certain procedures like endotracheal intubation and nebulized medication administration significantly increased the risk of transmission, while the use of N95 masks, gowns, and gloves substantially reduced the risk of healthcare workers contracting the virus.
Article Abstract
Objectives: To assess the risk of coronavirus transmission to healthcare workers performing aerosol-generating procedures and the potential benefits of personal protective equipment during these procedures.
Data Sources: MEDLINE, EMBASE, and Cochrane CENTRAL were searched using a combination of related MeSH terms and keywords.
Study Selection: Cohort studies and case controls investigating common anesthetic and critical care aerosol-generating procedures and transmission of severe acute respiratory syndrome coronavirus 1, Middle East respiratory syndrome coronavirus, and severe acute respiratory syndrome coronavirus 2 to healthcare workers were included for quantitative analysis.
Data Extraction: Qualitative and quantitative data on the transmission of severe acute respiratory syndrome coronavirus 1, severe acute respiratory syndrome coronavirus 2, and Middle East respiratory syndrome coronavirus to healthcare workers via aerosol-generating procedures in anesthesia and critical care were collected independently. The Risk Of Bias In Non-randomized Studies - of Interventions tool was used to assess the risk of bias of included studies.
Data Synthesis: Seventeen studies out of 2,676 yielded records were included for meta-analyses. Endotracheal intubation (odds ratio, 6.69, 95% CI, 3.81-11.72; p < 0.001), noninvasive ventilation (odds ratio, 3.65; 95% CI, 1.86-7.19; p < 0.001), and administration of nebulized medications (odds ratio, 10.03; 95% CI, 1.98-50.69; p = 0.005) were found to increase the odds of healthcare workers contracting severe acute respiratory syndrome coronavirus 1 or severe acute respiratory syndrome coronavirus 2. The use of N95 masks (odds ratio, 0.11; 95% CI, 0.03-0.39; p < 0.001), gowns (odds ratio, 0.59; 95% CI, 0.48-0.73; p < 0.001), and gloves (odds ratio, 0.39; 95% CI, 0.29-0.53; p < 0.001) were found to be significantly protective of healthcare workers from contracting severe acute respiratory syndrome coronavirus 1 or severe acute respiratory syndrome coronavirus 2.
Conclusions: Specific aerosol-generating procedures are high risk for the transmission of severe acute respiratory syndrome coronavirus 1 and severe acute respiratory syndrome coronavirus 2 from patients to healthcare workers. Personal protective equipment reduce the odds of contracting severe acute respiratory syndrome coronavirus 1 and severe acute respiratory syndrome coronavirus 2.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1097/CCM.0000000000004965 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Topic Modeling of Nursing Issues in the Media During 4 Emerging Infectious Disease Epidemics in South Korea: Descriptive Analysis.
J Med Internet Res
January 2025
College of Nursing Science, Kyung Hee University, Seoul, Republic of Korea.
Background: Emerging infectious disease disasters receive extensive media coverage and public attention. Nurse burnout and attrition peak during health crises such as pandemics. However, there is limited research on nursing issues related to repeated emerging infectious disease crises over time.
View Article and Find Full Text PDFThe association between abdominal ultrasound findings and clinical severity in MIS-C children with extracardiac symptoms.
Eur J Pediatr
January 2025
Department of Pediatric Intensive Care Unit, Dr. Behçet Uz Children Disease and Surgery Training and Research Hospital, University of Health Sciences, Izmir, Turkey.
Unlabelled: This study aimed to evaluate pathological findings on abdominal ultrasonography upon admission of children diagnosed with Multisystem Inflammatory Syndrome in Children (MIS-C) that were associated with a more severe disease course and the need for intensive care unit (ICU) admission. This retrospective and observational study was conducted between March 2020 and May 2022. Abdominal ultrasonography findings were evaluated in children diagnosed with MIS-C associated with SARS-CoV-2.
View Article and Find Full Text PDFA 21st-century update of Claude Bernard's Theory about the Constancy of the Internal Environment.
Neuropsychopharmacol Hung
December 2024
Municipal Clinic of Szentendre, Internal Medicine, Szentendre, Hungary.
The discovery of the functioning of intra- and extracellular ion compartments and cell membranes' operation opened the possibility of extending Claude Bernard's theory to intracellular ions. In contrast, by underestimating the role of ions, many misconceptions have prevailed. The author points out that maintaining the constancy of carbon dioxide is especially important.
View Article and Find Full Text PDF[Can CPAP prevent the progression of pediatric acute respiratory distress syndrome? A decade of experience in a Reference Center].
Andes Pediatr
October 2024
Facultad de Ciencias de la Vida, Universidad Andres Bello, Santiago, Chile.
Viral infections are the main cause of acute respiratory failure in infants, which can progress to acute respiratory distress syndrome (ARDS), with high morbidity and mortality, so it is essential to imple ment strategies that prevent this progression. Recently, it has been proposed that increased work of breathing would not only be a warning symptom during the evolution of acute respiratory failure, but also a mechanism for the progression of injury, both lungs and diaphragm, coining the concept of patient self-inflicted lung injury. Since the first reports of ARDS, the usefulness of the use of con tinuous positive airway pressure (CPAP) has been raised, a non-invasive respiratory support therapy with wide access and low cost, capable of improving oxygenation and work of breathing.
View Article and Find Full Text PDF[Effects of high-frequency volume-guaranteed ventilation in preterm newborns with respiratory distress syndrome: exploratory review].
Andes Pediatr
August 2024
Facultad de Salud, Universidad Santiago de Cali, Cali, Colombia.
Unlabelled: High-frequency oscillatory ventilation with volume guarantee (HFOV-VG) is a ventilatory mode that controls small tidal volumes at supraphysiological frequencies, potentially beneficial for preterm infants with respiratory distress syndrome (RDS).
Objective: To identify the physiological and clinical effects of HFOV-VG in preterm newborns with RDS, compared with conventional HFOV.
Method: Exploratory review of studies published between 2019 and 2023 of preterm newborns from 23 to 36 weeks of gestation with RDS, weighing ≥ 450g, with invasive HFOV support, using PRISMA flow diagram.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!