Doppelgänger dilemma: Leiomyoma versus uveal melanoma.

Am J Ophthalmol Case Rep

The New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.

Published: June 2021

Background: Ciliary body tumors can remain undetected and achieve large dimensions. Pigmented ciliary body tumors include: melanoma, leiomyoma and melanocytoma, however correct diagnosis may require tissue diagnosis with immunohistochemical stains.

Case Presentation: Two men presented with identical ciliochoroidal tumors. Both had darkly pigmented dome-shaped anterior uveal masses, exudative retinal detachments and transillumination shadowing. Ocular PET-CT imaging revealed that both were metabolically active consistent with a diagnosis of cancer. However, immunohistochemical examination revealed one a leiomyoma and the other melanoma.

Conclusion: Uveal leiomyoma can be an indistinguishable doppelgänger to ciliochoroidal melanoma, where the diagnosis can only be established by immunohistopathology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7973119PMC
http://dx.doi.org/10.1016/j.ajoc.2021.101040DOI Listing

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