AI Article Synopsis
- The study found a significant prevalence of dyslipidemia (56%) in patients with allergic rhinitis (AR).
- Higher levels of total immunoglobulin E (IgE) and interleukin-17A (IL-17A), along with sensitization to specific allergens like hay dust and mixed mites, were linked to an increased risk of dyslipidemia.
- These findings suggest that monitoring IgE and IL-17A levels could help identify AR patients at greater risk for dyslipidemia.
Article Abstract
Background: Although cumulative data strongly suggest an association between dyslipidemia and allergic disorders, especially asthma, evidence regarding allergic rhinitis (AR) is lacking. We aimed to assess frequency and associated risk factors of dyslipidemia among patients with AR.
Methods: The current study is a cross-sectional study that recruited 150 AR patients by systematic randomization. Blood samples for serum lipid profile, total immunoglobulin E (IgE) and serum interleukin-17A (IL-17A) were withdrawn from all patients.
Results: Dyslipidemia was prevalent in 84 AR patients (56%). Higher levels of total IgE, IL17-A, and sensitization to hay dust and mixed mites significantly increased the risk of dyslipidemia among AR patients by 1.004, 1.062, 4.057 and 3.652 respectively ( < 0.05).
Conclusion: High serum total IgE level, high serum IL-17A level, and sensitization to hay dust and mixed mites are independent risk factors for dyslipidemia among AR patients.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7937983 | PMC |
| http://dx.doi.org/10.1016/j.waojou.2021.100523 | DOI Listing |
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