In this work, we estimate the probability of an infected person infecting another person in the vicinity by coughing in the context of COVID-19. The analysis relies on the experimental data of Simha and Rao ["Universal trends in human cough airflows at large distances," Phys. Fluids , 081905 (2020)] and similarity analysis of Agrawal and Bhardwaj ["Reducing chances of COVID-19 infection by a cough cloud in a closed space," Phys. Fluids , 101704 (2020)] to determine the variation of the concentration of infected aerosols with some distance from the source. The analysis reveals a large probability of infection within the volume of the cough cloud and a rapid exponential decay beyond it. The benefit of using a mask is clearly brought out through a reduction in the probability of infection. The increase in the probability of transmission by a super-spreader is also quantified for the first time. At a distance of 1 m, the probability of infection from a super-spreader is found to be 185% larger than a normal person. Our results support the current recommendation of maintaining a 2 m distance between two people. The analysis is enough to be applied to the transmission of other diseases by coughing, while the probability of transmission of COVID-19 due to other respiratory events can be obtained using our proposed approach.
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http://dx.doi.org/10.1063/5.0041596 | DOI Listing |
Ann Am Thorac Soc
January 2025
The University of Tokyo, Department of Clinical Epidemiology and Health Economics, Bunkyo-ku, Tokyo, Japan.
Rationale: Although the guidelines generally omit routine antibiotic prophylaxis for diagnostic bronchoscopy, this recommendation is primarily based on studies with relatively small sample sizes conducted at single institutions. Moreover, the applicability of recent technical and procedural advancements to these guidelines remains uncertain.
Objectives: To evaluate whether oral prophylactic antibiotic administration for diagnostic bronchoscopy reduces post-bronchoscopy infections among non-infectious diseases in the current setting.
PLoS One
January 2025
School of Medicine, College of Health Sciences, Woldia University, Woldia, Ethiopia.
Background: Multiple studies across Ethiopia have investigated the occurrence of DKA, showing significant variations and conflicting findings. This systematic review and meta-analysis seek to consolidate the overall prevalence of diabetic ketoacidosis and its associated factors in the Ethiopian context.
Methods: The study adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P) guidelines.
PLoS Med
January 2025
Division of Infectious Diseases, Department of Medicine II, Medical Centre and Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany.
Background: Self-reported health problems following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are common and often include relatively non-specific complaints such as fatigue, exertional dyspnoea, concentration or memory disturbance and sleep problems. The long-term prognosis of such post-acute sequelae of COVID-19/post-COVID-19 syndrome (PCS) is unknown, and data finding and correlating organ dysfunction and pathology with self-reported symptoms in patients with non-recovery from PCS is scarce. We wanted to describe clinical characteristics and diagnostic findings among patients with PCS persisting for >1 year and assessed risk factors for PCS persistence versus improvement.
View Article and Find Full Text PDFPLoS One
January 2025
Jinan University, Guangzhou, China.
Objective: This study aimed to develop and validate a nomogram to predict the risk of sepsis in non-traumatic subarachnoid hemorrhage (SAH) patients using data from the MIMIC-IV database.
Methods: A total of 803 SAH patients meeting the inclusion criteria were randomly divided into a training set (563 cases) and a validation set (240 cases). Independent prognostic factors were identified through forward stepwise logistic regression, and a nomogram was created based on these factors.
Ann Med
December 2025
Department of Joint and Sports Medicine, Zhongnan Hospital, Wuhan University, Wuhan, China.
As life expectancy among patients infected with the human immunodeficiency virus (HIV) increases, a growing number of complications have been observed. This population displays an elevated risk of ischemic necrosis of the femoral head in comparison to the general population, which may be attributed to HIV infection, antiretroviral medication use, and hormone application. Patients infected with the human immunodeficiency virus (HIV) who also have necrosis of the femoral head tend to present at an earlier age, with a rapid disease progression and a high incidence of bilateral onset.
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