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Setting a research agenda for examining early risk for elevated cognitive disengagement syndrome symptoms using data from the ABCD cohort.
Eur Child Adolesc Psychiatry
March 2025
Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Little research has examined early life risk for symptoms of cognitive disengagement syndrome (CDS) despite a well-established literature regarding co-occurring outcomes (e.g., attention-deficit/hyperactivity disorder).
View Article and Find Full Text PDFBridging the gap between research and decision making: A European survey to enhance cooperation in wastewater-based epidemiology (WBE) for illicit drugs.
Public Health
February 2025
European Union Drugs Agency, Lisbon, Portugal.
Objectives: Illicit drug use presents a significant challenge to global health and public safety, requiring innovative and effective monitoring strategies. This study aimed to evaluate the current landscape of wastewater-based epidemiology (WBE) for monitoring illicit drugs in Europe, focusing on collaboration, current practices, and barriers, while identifying opportunities for improvement.
Study Design: Cross-sectional survey-based study.
Assessing pharmaceutical and illicit drugs abuse in a university environment through wastewater analysis.
Sci Total Environ
February 2025
Analytical Chemistry Department, Universitat de València, Dr. Moliner 50, 46100 Burjassot, Spain. Electronic address:
Monitoring the presence of illicit and pharmaceutical drugs in wastewater has emerged as a powerful tool for determining drug consumption patterns and trends within a specific population group. In this study, an analytical method has been developed to determine the presence of forty psychoactive substances, including stimulants, benzodiazepines, antidepressants, and opioids, in wastewater. The proposed approach combines in-situ wastewater single sampling, solid-phase extraction, and ultra-high performance liquid chromatography coupled with tandem mass spectrometry determination.
View Article and Find Full Text PDFUsing illicit drugs alone in Vancouver, Canada: a gender-based analysis.
Subst Abuse Treat Prev Policy
February 2025
British Columbia Centre On Substance Use, Vancouver, BC, Canada.
Objectives: Canada continues to experience an epidemic of toxic drug-related overdose deaths. Public health messaging emphasizes the dangers of using drugs alone as it restricts timely overdose response or renders it impossible, yet this practice remains prevalent among people who use drugs. While drug use practices and associated harms are known to be highly gendered, little is known about how factors shaping solitary drug use may differ across genders (including cisgender men, cisgender women, transgender women, Two-Spirit people and gender diverse people).
View Article and Find Full Text PDFOut-of-Hospital Cardiac Arrest in Apparently Healthy, Young Adults.
JAMA
February 2025
Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, University of California, San Francisco.
Importance: Out-of-hospital cardiac arrest incidence in apparently healthy adults younger than 40 years ranges from 4 to 14 per 100 000 person-years worldwide. Of an estimated 350 000 to 450 000 total annual out-of-hospital cardiac arrests in the US, approximately 10% survive.
Observations: Among young adults who have had cardiac arrest outside of a hospital, approximately 60% die before reaching a hospital (presumed sudden cardiac death), approximately 40% survive to hospitalization (resuscitated sudden cardiac arrest), and 9% to 16% survive to hospital discharge (sudden cardiac arrest survivor), of whom approximately 90% have a good neurological status (Cerebral Performance Category 1 or 2).
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