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Triple Therapy IDP-126 Gel for Acne Treatment: A Systematic Review and Meta-Analysis.
Cureus
November 2024
Dermatology, Vivida Dermatology, Las Vegas, USA.
Acne vulgaris (AV) is a common dermatological condition that ranges from mild comedones to severe inflammatory nodules and scarring. Effective management is essential for improving patients' quality of life. The recent FDA approval of IDP-126 (Cabtreo™), a novel triple-combination gel, meets these needs by combining clindamycin phosphate, benzoyl peroxide, and adapalene into a single formulation.
View Article and Find Full Text PDFGender-Related Characterization of Acne in Chinese: A Multiple-Center Cross-Sectional Survey on 13085 Cases.
Clin Cosmet Investig Dermatol
December 2024
Department of Dermatology, The People's Hospital of Baoshan/Fifth Affiliated Hospital of Dali University, Baoshan, Yunnan, People's Republic of China.
Background: Acne is a common inflammatory dermatosis. Although gender-related differences in prevalence and age of onset have been documented. Other gender-related characteristics of acne have not been well elucidated yet.
View Article and Find Full Text PDFA Mixture of Water-Soluble Polysaccharides Reduces Caspase-1 and IL-1β Inflammatory Responses by in vitro in Reconstructed Human Epidermis (RHE).
Clin Cosmet Investig Dermatol
November 2024
Research, Vantage, Warren, NJ, USA.
Introduction: It is well established that () is a common skin commensal microorganism that has been linked to acne. In acne flare-ups, can be found in abundant levels within the inflammatory lesions (called comedones) associated with the skin disease. Recently, it was reported that 3D reconstructed human epidermis (RHE) treated with viable cultures of can elicit β-defensin antimicrobial peptide responses in the skin and can weaken the skin barrier of the RHE after three days of exposure to .
View Article and Find Full Text PDFPerianal Comedones: A Variant of Hidradenitis Suppurativa or an Isolated Entity? Five-Case Report.
Actas Dermosifiliogr
November 2024
Departamento de Dermatología, Hospital Universitari Germans Trias i Pujol, Institut Investigació Germans Trias i Pujol (IGTP), Badalona, Barcelona, España.
Although comedones are a prevalent entity in multiple skin diseases, their perianal location as a cluster is a rare finding. We describe 5 patients with grouped perianal comedones who developed the lesions in adulthood and were treatment-naïve in the perianal area. Four of them had had inflammatory lesions in armpits and groins.
View Article and Find Full Text PDFAcneiform lesions in a 57-year-old woman.
Int J Dermatol
November 2024
Department of Dermatology, Rush University Medical Center, Chicago, Illinois, USA.
A 57-year-old woman on leflunomide with a history of chronic obstructive pulmonary disease and rheumatoid arthritis presented with multiple flesh-colored to hyperpigmented dome-shaped papules, scattered comedones, and underlying scarring on bilateral cheeks and chin. These dermatologic manifestations, laboratory evaluation, and punch biopsy led to a final diagnosis of acneiform or comedonal discoid lupus erythematosus (ACDLE). For patients with acneiform or comedonal lesions, ACDLE should be considered if the lesions do not improve with conventional treatment for acne vulgaris.
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