The implant-supported magnet-retained silicon orbital prosthesis (SOP) was reported as a reliable method to restore the health-related quality of life of patients who underwent facial resection and reconstruction surgery. Currently, fabrication usually requires a long production time and a high level of expertise. Moreover, due to the complex features of facial defects, accurate prosthesis requires many patient fittings.The prosthesis was designed to repair a complex orbital defect. A reproducible major mold was used to make various silicone prototypes with differences in margin design, silicone shade, and artificial eye's details. The most suitable silicone prototype was chosen for the finalization of the SOP. The patient reported the satisfaction with the function, prosthesis retention, and esthetic restoration.This clinical study showed that the new technique using a reproducible major mold can allow the fabrication of various prototypes, save time during fitting, and help in improving personalized fabrication of the SOP.
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http://dx.doi.org/10.1097/SCS.0000000000007393 | DOI Listing |
Objectives: The pelvic floor muscle (PFM) plays a major role in sexual and urinary functions. No objective method exists to measure the PFM in male. This study evaluated the reliability of male PFM volume using three-dimensional computed tomography (3D-CT).
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January 2025
Faculty of Physics, M.V. Lomonosov Moscow State University, 1-2 Leninskie Gory, Moscow, 119991, Russia.
The issue of variability introduced into blood plasma and serum analysis by preanalytical procedures is the major obstacle to obtaining accurate and reproducible results. While the question of how to overcome this issue has been discussed in biochemical detection of analytes and omics technologies, its relevance to the field of optical spectroscopy remains mostly unexplored. In this work, we evaluated the freeze-thaw cycle (FTC)-induced alternations in blood serum optical properties by means of autofluorescence and Raman spectroscopy, including surface-enhanced Raman spectroscopy (SERS).
View Article and Find Full Text PDFEur J Trauma Emerg Surg
January 2025
Division of Neurosurgery, Department of Surgery, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Background: Traumatic brain injury (TBI) is considered a major cause of death globally, resulting from trauma. Decompressive craniectomy (DC) may improve functional outcomes in patients with TBI and its associated complications. This study was designed to determine safety and efficacy of DC in improving clinical outcomes in TBI patients compared to standard therapy.
View Article and Find Full Text PDFAims: This study aimed to determine the robustness, reproducibility and representativeness of the landmark Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (AF) (ARISTOTLE) and Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism Trial in AF (ROCKET AF) randomised trials through replication in an observational AF patient registry.
Methods And Results: Patients from the Global Anticoagulant Registry in the FIELD (GARFIELD)-AF registry treated with apixaban, rivaroxaban or vitamin K antagonist (VKA) were assessed for eligibility for the ARISTOTLE and ROCKET AF trials. HRs of apixaban and rivaroxaban versus comparator for stroke/systemic embolism, major bleeding and all-cause mortality within 2 years follow-up were calculated using propensity score overlap-weighted Cox models.
Background: Several studies evaluated peripheral and cerebrospinal fluid (CSF) mtDNA as a putative biomarker in neurodegenerative diseases, often yielding inconsistent findings. We systematically reviewed the current evidence assessing blood and CSF mtDNA levels and variant burden in Parkinson's disease (PD), Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS). Multiple sclerosis (MS) was also included as a paradigm of chronic neuroinflammation-driven neurodegeneration.
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