Huang et al. (2021) identified a mechanism acting through the arginine methyltransferase PRMT6 that stabilizes the interaction of RCC1 with chromatin, promoting cell proliferation and tumorigenicity. Targeting this mechanism might enhance the treatment of tumors such as glioblastoma.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.molcel.2021.02.026 | DOI Listing |
Publication Analysis
Top Keywords
cell proliferation
8
focused prmt6
4
prmt6 drives
4
drives localization
4
localization rcc1
4
rcc1 chromosomes
4
chromosomes facilitate
4
facilitate mitosis
4
mitosis cell
4
proliferation tumorigenesis
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!