The effects of attentional focus (AF) instruction were examined in a reciprocal aiming task implemented in a 3-dimensional, fully immersive virtual environment (VE). Within the VE, participants (N = 19) moved a cube between two targets at two paces (750 ms and 500 ms) while being asked to focus externally (EXF) and internally (INF). Performance accuracy was measured as two-dimensional error and its variability between the center of the target to the center of the cube and one-dimensional bias (undershooting/overshooting behavior in the anteroposterior and mediolateral directions). The results indicated better performance, specifically greater accuracy and lower one-dimensional bias in the anteroposterior direction when adopting an EXF compared to an INF. Our findings reveal that the beneficial effects of an EXF on motor performance are not restricted movements within physical environments only but also work in VE. This has implications for rehabilitation and training protocols in VE.

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