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http://dx.doi.org/10.1007/s00216-021-03276-w | DOI Listing |
Alzheimers Dement
December 2024
University of Missouri, Columbia, MO, USA.
Background: Despite data showing nutritional interventions high in antioxidant/anti-inflammatory properties (anthocyanin-rich foods such as blueberries/elderberries) may decrease risk of memory loss and cognitive decline, evidence for such effects in mild cognitive impairment (MCI) patients is limited. Therefore, we examined preliminary effects of American elderberry (Sambucus nigra canadensis) juice on cognition and inflammatory markers in MCI patients in a double-blind placebo-controlled trial.
Method: MCI patients (N = 24, M = 76.
Alzheimers Dement
December 2024
Global Brain Health Institute (GBHI), Trinity College Dublin (TCD), Dublin, Ireland.
Background: Socioeconomic disparities (SED) influence brain health and dementia. Latin America (LA) is characterized by high SED and a disproportionate prevalence of Alzheimer's disease (AD) and frontotemporal lobe degeneration (FTLD) compared to high-income populations like the United States (US). However, the impact of SED on brain reserve across neurocognitive pathways related to aging and dementia in LA remains unknown.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Memory and Aging Center, UCSF Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.
Background: The earliest cognitive manifestations of asymptomatic and prodromal familial frontotemporal dementia (f-FTD) mutation carriers are still being characterized. Patients with symptomatic FTD are known to be error prone, particularly on tasks of executive function, but little is known about the frequency or predictive utility of these errors in the earliest stages of f-FTD. The current study compared error rates on executive functioning tasks in controls and asymptomatic and prodromal mutation carriers and investigated whether errors predict worsening clinical status as follow up.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
NIA-Layton Aging & Alzheimer's Disease Research Center, Portland, OR, USA.
Background: Agitation is one of the most challenging behaviors exhibited by people with cognitive decline, causing distress in caregivers, earlier placement into long-term care and faster disease progression. In order to better manage agitated behaviors in people with cognitive decline, it is important to identify associated factors. The MODERATE (Monitoring Dementia-Related Agitation Using Technology Evaluation) study aims to characterize agitation using technology and identify precipitants (behavioral or environmental) of agitation.
View Article and Find Full Text PDFClin Kidney J
January 2025
Healthy Aging Research Center, Chang Gung University, Taoyuan City, Taiwan.
Background: Damage to brain white matter often occurs in individuals with chronic kidney disease, which might be related to their cognitive decline. This study aims to investigate tract-specific white matter damage in patients with end-stage kidney disease by using fixel-based analysis.
Methods: Images of 31 end-stage kidney disease patients and 16 normal controls (aged: 61.
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