The Indian health care system lacks the infrastructure to meet the health care demands of the country. Physician and nurse availability is 30 and 50% below WHO recommendations, respectively, and has led to a steep imbalance between the demand for health care and the infrastructure available to support it. Among other concerns, India still struggles with challenges like undernutrition, with 38% of children under the age of five being underweight. Despite these challenges, technological advancements, mobile phone ubiquity and rising patient awareness offers a huge opportunity for artificial intelligence to enable efficient healthcare delivery, by improved targeting of constrained resources. The Saathealth mobile app provides low-middle income parents of young children nflwith interactive children's health, nutrition and development content in the form of an entertaining video series, a gamified quiz journey and targeted notifications. The app iteratively evolves the user journey based on dynamic data and predictive algorithms, empowering a shift from reactive to proactive care. Saathealth users have registered over 500,000 sessions and over 200 million seconds on-app engagement over a year, comparing favorably with engagement on other digital health interventions in underserved communities. We have used valuable app analytics data and insights from our 45,000 users to build scalable, predictive models that were validated for specific use cases. Using the Random Forest model with heterogeneous data allowed us to predict user churn with a 93% accuracy. Predicting user lifetimes on the mobile app for preliminary insights gave us an RMSE of 25.09 days and an R2 value of 0.91, reflecting closely correlated predictions. These predictive algorithms allow us to incentivize users with optimized offers and omni-channel nudges, to increase engagement with content as well as other targeted online and offline behaviors. The algorithms also optimize the effectiveness of our intervention by augmenting personalized experiences and directing limited health resources toward populations that are most resistant to digital first interventions. These and similar AI powered algorithms will allow us to lengthen and deepen the lifetime relationship with our health consumers, making more of them effective, proactive participants in improving children's health, nutrition and early cognitive development.
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http://dx.doi.org/10.3389/frai.2020.544972 | DOI Listing |
Pediatr Blood Cancer
January 2025
Division of Hematology, Children's National Hospital, Washington, District of Columbia, USA.
Background: Sickle cell disease (SCD) confers neurological risks that contribute to cognitive and academic difficulties. Clinical guidelines state that cognition should be monitored using signaling questions. However, evidence is lacking regarding the extent to which signaling questions accurately identify children with cognitive issues.
View Article and Find Full Text PDFBJOG
January 2025
Women's, Children's and Adolescents' Health Program, Burnet Institute, Melbourne, Australia.
Background: Evidence suggests L-arginine may be effective at reducing pre-eclampsia and related outcomes. However, whether L-arginine can prevent or only treat pre-eclampsia, and thus the target population and timing of initiation, remains unknown.
Objectives: To evaluate the effects of L-arginine and L-citrulline (precursor of L-arginine) on the prevention and treatment of pre-eclampsia.
J Paediatr Child Health
January 2025
Department of Neonatology, University of Health Sciences, Ankara Bilkent City Hospital, Ankara, Turkey.
Objective: To evaluate the incidence of thin catheter surfactant administration (TCA) failure and compare short and long-term neonatal outcomes who failed TCA or did not.
Design: Single-center retrospective cohort study. Infants between 25 and 30 weeks of gestational age with respiratory distress syndrome and receiving 200 mg/kg poractant alfa via thin catheter administration were included.
Schizophr Bull
January 2025
Orygen, Parkville, Victoria 3052, Australia.
Background: Although attention deficit hyperactivity disorder (ADHD) is known to be common in psychotic disorders, reported prevalence rates vary widely, with limited understanding of how different factors (eg, assessment methods, geographical region) may be associated with this variation. The aim was to conduct a systematic review and meta-analysis to determine the prevalence of ADHD in psychotic disorders and factors associated with the variability in reported rates.
Study Design: Searches were conducted in MEDLINE, Embase, PsycINFO, CINAHL, and Scopus in May 2023.
NPJ Biofilms Microbiomes
January 2025
A*STAR Skin Research Labs (A*SRL), Agency for Science, Technology, and Research (A*STAR) & Skin Research Institute of Singapore (SRIS), Singapore, Republic of Singapore.
Sebaceous free fatty acids are metabolized by multiple skin microbes into bioactive lipid mediators termed oxylipins. This study investigated correlations between skin oxylipins and microbes on the superficial skin of pre-pubescent children (N = 36) and adults (N = 100), including pre- (N = 25) and post-menopausal females (N = 25). Lipidomics and metagenomics revealed that Malassezia restricta positively correlated with the oxylipin 9,10-DiHOME on adult skin and negatively correlated with its precursor, 9,10-EpOME, on pre-pubescent skin.
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