Different memory systems operate in parallel to support behaviour. To evaluate procedural and reference subcategories of long-term memory as early as possible in the mouse, the Helico Maze (HM) was developed. BALB/c AnNCrl (BALB), C57BL/6JRj (C57) and DBA/2 JRj (DBA) mice were trained on this new maze. The three strains learned how to use the HM (procedural memory), and they then learned and remembered four odour-reward associations (reference memory). The three strains differed in the number of correct responses. BALB mice showed better performance than C57 and DBA mice. The results of the first block of each session revealed that only the BALB and C57 mice remembered the odour-reward associations. DBA mice needed to relearn the associations each day. With this new apparatus, the number of olfactory cue-reward associations was increased from 2 to 4 in comparison to a previous olfactory tubing maze. Consequently, a supplementary effort of memory was required, and the chance level was decreased from 50 % to 25 %. Thus, in several important respects, the HM can be considered to measure the hippocampus-dependent behaviour of the mouse, allowing to study, as early as possible in young mice, the different subcategories of long-term memory, such as those observed in humans.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.bbr.2021.113242 | DOI Listing |
J Med Internet Res
December 2024
Research Unit of Health Sciences and Technology (HST), University of Oulu, Oulu, Finland.
Background: Cerebrovascular diseases (CVDs) are a major and potentially increasing burden to public health. Digital health interventions (DHIs) could support access to and provision of high-quality health care (eg, outcomes, safety, and satisfaction), but the design and development of digital solutions and technologies lack the assessment of user needs. Research is needed to identify opportunities to address health system challenges and improve CVD care with primary users of services as the key informants of everyday requirements.
View Article and Find Full Text PDFBMC Res Notes
November 2024
Community Based Psychiatric Care Research Center, Department of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.
Background: Providing care to trauma patients in pre-hospital emergencies is a vital and life-sustaining factor for individuals. This study was conducted to percept of pre-hospital emergency personnel regarding trauma patient care.
Methods: This qualitative study was done using a conventional content analysis method that employed purposive sampling technique.
JAMA Netw Open
November 2024
Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada.
Allergol Select
November 2024
Department of Oto-Rhino-Laryngology. Head and Neck Surgery, Ulm University Medical Center, Ulm.
Background And Objectives: Patients with rare diseases like hereditary angioedema (HAE) are usually referred to an angioedema center to ensure guideline-compliant and experience-based therapy. Even though there are established guidelines and several approved therapeutics, there are still open questions and situations in the daily care of HAE patients, where an exchange between centers is needed.
Materials And Methods: A survey was conducted among physicians from German angioedema centers regarding challenges and issues in everyday HAE treatment.
Int J Nurs Stud
January 2025
School of Nursing, Lanzhou University, Gansu Province 730011, China. Electronic address:
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!