AI Article Synopsis
- The study evaluated the effectiveness of asymmetric progressive thickness intrastromal corneal ring segments (PT-ICRS) in improving visual acuity and corneal shape in patients with asymmetric duck phenotype keratoconus.
- At 1, 3, and 6 months after implantation, significant improvements were observed in uncorrected and corrected distance visual acuity as well as a reduction in refractive errors and keratometry measurements.
- The findings suggest that PT-ICRS is a safe and effective treatment option for enhancing visual outcomes and reducing corneal irregularities in this patient group.
Article Abstract
Purpose: To evaluate clinical outcomes in patients with asymmetric duck phenotype keratoconus implanted with asymmetric progressive thickness intrastromal corneal ring segments (PT-ICRS, Keraring AS, Mediphacos, Belo Horizonte, Brazil), and to demonstrate improved visual acuity and symmetry in corneal flattening.
Methods: This single-center, retrospective, observational study evaluated the clinical outcomes at 1, 3, and 6 months after implantation of PT-ICRS in patients with duck phenotype keratoconus. After creating the intrastromal tunnel with a femtosecond laser, one 160-degree arc length PT-ICRS, either 150/250 µm or 200/300 µm, was implanted. Changes in uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction (MR), manifest refraction spherical equivalent (MRSE), mean keratometry (Kmean), maximum keratometry (Kmax), Coma@5mm, and manifest and topographical astigmatism were documented.
Results: The study cohort included 23 eyes of 17 patients with a mean age of 24.6 years. From baseline to 6 months following implantation, mean UDVA improved from 0.70 logarithm of the minimum angle of resolution (logMAR) (20/100 Snellen) to 0.22 logMAR (20/33 Snellen), CDVA improved from 0.33 logMAR (20/42 Snellen) to 0.14 logMAR (20/27 Snellen), the mean sphere and MRSE decreased from -1.05 diopters (D) and -2.70 D to -0.25 D and -0.80 D, respectively, and the Kmean and Kmax improved from 46.5 D and 53.7 D to 44.6 D and 48.7 D, respectively.
Conclusions: The Keraring AS ICRS offers a safe, effective means of improving visual acuity while reducing refractive error, mean and max keratometry, and aberrations in patients with duck phenotype keratoconus.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/11206721211001722 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development and application of a cGPS 20K liquid-phase SNP microarray in Jiaji ducks.
Poult Sci
December 2024
Institute of Animal Science and Veterinary Medicine, Hainan Academy of Agricultural Sciences, Hainan, Haikou 571101, PR China. Electronic address:
In order to provide a low-cost, high efficient, and highly accurate tool for molecular breeding of Jiaji ducks, we constructed a cGPS(Genotyping by Pinpoint Sequencing of captured targets) 20 K liquid-phase microarray using resequencing data from this valuable poultry breed for the first time. The microarray contains 20,327 high-quality snp loci, mainly from the 30 Jiaji duck resequencing samples collected in this study, and some loci were supplemented from the 135 duck resequencing data from KUNMING INSTITUTE OF ZOOLOGY.CAS.
View Article and Find Full Text PDFtRNA-Ser-UGA efficiently promotes the rapid release of duck hepatitis A virus from infected enterocytes and its remote dissemination to hepatocytes.
Poult Sci
December 2024
Engineering Research Center of Southwest Animal Disease Prevention and Control Technology, Ministry of Education of the People's Republic of China, Sichuan Agricultural University, China; Key Laboratory of Animal Disease and Human Health of Sichuan Province, Sichuan Agricultural University, China; Institute of Veterinary Medicine and Immunology, College of Veterinary Medicine, Sichuan Agricultural University, China. Electronic address:
Enterocytes are a necessary portal for fecal-oral transmission of viruses, including duck hepatitis A virus (DHAV), that act on the absorption of amino acids (AAs). We note that the rapid death of ducklings caused by DHAV is likely due to its rapid release from enterocytes. However, the underlying mechanism driving the release of DHAV remains poorly understood.
View Article and Find Full Text PDFTranscriptome analysis reveals the regulatory mechanism of myofiber development in male and female black Muscovy duck at different ages.
Front Vet Sci
November 2024
Institute of Animal Husbandry and Veterinary Medicine, Jiangxi Academy of Agricultural Sciences, Jiangxi Poultry Engineering Technology Research Center, Jiangxi Poultry Breeding Engineering Laboratory, Nanchang, Jiangxi, China.
Introduction: Sexual dimorphism in Muscovy ducks results in substantial differences in muscle development potential between males and females, leading to significant variations in growth rates and body weights throughout their development.
Methods: This study aimed to investigate the regulatory mechanisms underlying the differences in muscle development between genders in black Muscovy ducks, we analyzed the phenotypic characteristics and transcriptome profiles of breast muscles in male and female black Muscovy ducks at different developmental stages (postnatal days 28, 42, and 70).
Results: In the analysis of tissue physical morphology, the results showed that females exhibit larger myofiber diameters and lower myofiber densities compared to males at postnatal day 42 ( < 0.
Integration of GWAS and transcriptomic analyses reveal candidate genes for duck gonadal development during puberty onset.
BMC Genomics
November 2024
Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, 611130, Sichuan, P.R. China.
Background: Puberty onset signifies the beginning of sexual maturation and reproductive phase in poultry indeed, and plays an essential role in genetics and breeding. Studying gonadal development is one of the important approaches to exploring the genetic mechanism of puberty onset.
Result: In our study, the phenotype data of the testes and ovaries of the 120-day-old Nonghua duck showed a large coefficient of variation, indicating that their gonads were in different developmental states.
Pathogenicity and identification of host adaptation genes of the avian pathogenic O145 in duck.
Front Cell Infect Microbiol
November 2024
Institute of Animal Husbandry and Veterinary Science, Jiangxi Academy of Agricultural Sciences, Nanchang, China.
Article Synopsis
- APEC O145 is a significant bacterial pathogen impacting poultry in China, with recent studies indicating its rise as a predominant serogroup.
- A virulent strain called NC22 was analyzed to understand its pathogenic mechanisms through whole-genome sequencing and by observing its behavior in duck liver compared to lab cultures.
- The study found that NC22 infection led to severe symptoms in ducks and identified 87 differentially expressed genes related to metabolism and host adaptation, shedding light on the complex interactions between APEC O145 and its hosts.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!