Purpose: Intervention development guidelines suggest that behavioural interventions benefit from being theory-based. Minority populations typically benefit less from asthma self-management interventions, and the extent to which appropriate theory has been used for culturally tailored interventions has not been addressed. We aimed to determine theory use and theoretical domains targeted in asthma self-management interventions for South Asian and Black populations.
Methods: We systematically searched electronic databases, research registers, manually searched relevant journals and reference lists of reviews for randomised controlled trials of asthma self-management for South Asian and Black populations, and extracted data using the Theory Coding Scheme to inform if/how theory was used and explore its associations with asthma outcomes, and the Theoretical Domains Framework was used to identify targeted theoretical domains and its relationship to effectiveness of asthma outcomes.
Results: 20 papers (19 trials) were identified; theory was not extensively used in interventions. It was unclear whether theory use or theoretical domains targeted in interventions improved asthma outcomes. South Asian interventions included 'behavioural regulation', while 'reinforcement' was mostly used in African American interventions. 'Knowledge' was central for all populations, though there were differences related to 'environmental context and resources' e.g., language adaptations for South Asians; asthma resources provided for African Americans. Author descriptions of interventions targeting providers were limited.
Conclusions: There was little evidence of theory-based approaches used in cultural interventions for asthma self-management. Demystifying theoretical concepts (and cultural interpretations of constructs) may provide clarity for 'non-experts', enabling mainstream use of theory-driven approaches in intervention development.
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http://dx.doi.org/10.1111/bjhp.12518 | DOI Listing |
PEC Innov
June 2025
Department of Respiratory Medicine, Royal Devon and Exeter Hospital, University of Exeter, Exeter, United Kingdom.
Objective: To assess the feasibility and acceptability of adapting a psychoeducation course (Body Reprogramming) for severe asthma and finding suggestions for improvement.
Methods: Severe asthma patients were recruited from a single centre and enrolled in an online group-based course. Each course consisted of four sessions: introduction to BR, stress, exercise, and diet.
Sci Immunol
January 2025
Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Human recombination-activating gene (RAG) deficiency can manifest with distinct clinical and immunological phenotypes. By applying a multiomics approach to a large group of -mutated patients, we aimed at characterizing the immunopathology associated with each phenotype. Although defective T and B cell development is common to all phenotypes, patients with hypomorphic variants can generate T and B cells with signatures of immune dysregulation and produce autoantibodies to a broad range of self-antigens, including type I interferons.
View Article and Find Full Text PDFWorld Allergy Organ J
December 2024
Novartis Pharma GmbH, Nuernberg, Germany.
Background: Lacking causal treatment options in most cases, severe IgE-mediated food allergies (IgE-FA) are associated with a high burden of disease due to permanent risk of anaphylactic reactions after accidental allergen ingestion. To date, only few data comparing health resources and burden of disease between the pediatric and adult population are available.
Objective: Our survey aimed to assess the care situation of pediatric and adult patients with severe, self-reported physician-diagnosed IgE-FA.
J Asthma
January 2025
Nottingham Asthma Centre, Nottingham Respiratory Research Unit, University of Nottingham, UK.
Rationale: Asthma attacks (AA) are potentially life-threatening complications of asthma associated with high levels of morbidity, mortality and rising healthcare costs. Patient experience, impact and understanding of AA is poorly described in the literature. Enhanced understanding will identify unmet needs in asthma care and support the development of improved personalized strategies for managing and preventing attacks.
View Article and Find Full Text PDFChildren (Basel)
December 2024
Department of Pediatrics, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
A comprehensive review and meta-analysis were conducted with the purpose of determining the extent to which asthma is prevalent among children in Saudi Arabia. This was done with the intention of addressing the dearth of data at the national level regarding this significant health concern. The study included data from PubMed, Embase, Cochrane Library, and Google Scholar for the period 2015-2024, focusing on studies that reported the prevalence of asthma among children in the country.
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