AI Article Synopsis
- Central hypovolemia triggers enhanced left ventricular (LV) untwisting as a way to compensate for reduced stroke volume during orthostatic stress.
- This compensatory mechanism helps maintain heart function when blood flow to the heart is diminished while standing up.
- Both athletes and those with low fitness may experience orthostatic intolerance because their LV untwisting does not respond effectively to central hypovolemia.
Article Abstract
Augmentation of left ventricular (LV) untwisting due to central hypovolemia is likely to be a compensatory mechanism for maintaining stroke volume, which is reduced by a decrease in cardiac filling during orthostatic stress. Orthostatic intolerance observed in both high and low fitness levels may be explained by the impaired response of LV untwisting due to central hypovolemia.
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| http://dx.doi.org/10.1249/JES.0000000000000247 | DOI Listing |
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