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Congenital extrahepatic portocaval malformation: Rare but potentially treatable cause of pulmonary hypertension. | LitMetric

Congenital extrahepatic portocaval malformation: Rare but potentially treatable cause of pulmonary hypertension.

Indian Heart J

Children's' Heart Center, Second Floor, Kokilaben Dhirubai Ambani Hospital and Research Center, Rao Achyut Rao Patwardhan Marg, Four Bunglows, Andheri West, Mumbai, Maharashtra, 400053, India.

Published: July 2021

AI Article Synopsis

Article Abstract

Objective: Abernethy malformation (congenital extrahepatic portosystemic shunt) is a rare anomaly of the splanchnic venous system. Though rare, it is an important cause of pulmonary artery hypertension (PAH) which is often missed. All patients with PAH should be carefully evaluated for presence of Abernethy malformation before labelling them as Idiopathic PAH.

Methods: This is a retrospective analysis of prospectively collected data. We reviewed the data of all patients referred to our center for evaluation of PAH. 10 patients were diagnosed to have an extrahepatic portocaval malformation. We reviewed their presentation, diagnosis, catheterization data, intervention and their outcome along with review of literature.

Results: 10/104 patients with pulmonary hypertension and no intra or extracardiac shunt were found to have extrahepatic portocaval shunt (EHPCS). 3 patients had EHPCS type 1 and 7 had type 2 EHPCS. 6/7 patient with EHPCS type 2 underwent closure of the shunt. There was no procedure related complication. There was one death 3 months post procedure and one patient who was advised surgical closure was lost to follow up. Closure of the shunt resulted in normalization of the pulmonary artery pressures in 4/5 patients.

Conclusion: Congenital portosystemic malformations form an important and potentially treatable cause of pulmonary hypertension.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961257PMC
http://dx.doi.org/10.1016/j.ihj.2020.12.015DOI Listing

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