Aminoacylated ergosterol such as 1-ergosteryl aspartate (Erg-Asp) is a new lipid component recently discovered in fungi. In order to study physiological functions of this novel sterol derivative and to develop potential antifungal agents, we established the method to synthesize aminoacylated ergosterol derivatives. Herein, we report the synthesis of Erg-Asp as well as some other aminoacylated ergosterols (Erg-Gly, Erg-Ala, Erg-Leu, Erg-Ile, and Erg-Val) using Boc protected amino acids.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.steroids.2021.108823 | DOI Listing |
Publication Analysis
Top Keywords
aminoacylated ergosterols
8
lipid component
8
aminoacylated ergosterol
8
synthesis aminoacylated
4
ergosterols lipid
4
component fungi
4
fungi aminoacylated
4
ergosterol 1-ergosteryl
4
1-ergosteryl aspartate
4
aspartate erg-asp
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!