AI Article Synopsis
- This study examined clinical samples from patients in Syria and Turkey suffering from cutaneous leishmaniasis, focusing on the genetic makeup through ITS1 sequences.
- All sequences identified were of the Leishmania tropica species, contributing to a larger genetic diversity analysis using data from GenBank.
- The findings suggest a complex distribution of L. tropica haplotypes, with some being widespread while others are limited to specific areas, possibly linked to different vectors or animal reservoirs.
Article Abstract
In this study, we characterized a collection of clinical samples obtained from Syrian and Turkish patients with cutaneous leishmaniasis using internal transcribed spacer 1 (ITS1) sequences. All obtained sequences belonged to Leishmania tropica. Combining them with those available from GenBank allowed us performing a broad-scale analysis of genetic diversity for this species. We demonstrated that L. tropica has a complex phylogeographic pattern with some haplotypes being widespread across endemic countries and others restricted to particular regions. We hypothesize that at least some of them may be associated with alternative vectors or animal reservoirs.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.actatropica.2021.105888 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!