Preschool children aged 3-6 years are vulnerable to exposed to particulate matter ("PM10" and "PM2.5"). It is required in evaluating the risk based on dose of preschool children. Microenvironments which preschool children mainly visited were classified. Inhalation type was adapted in each microenvironment in consideration of intensity of activity. The exposure scenario was described as preschool children had been living in Seoul, South Korea, and dose was calculated by considering time-activity-pattern with major microenvironments and inhalation type of preschool children for 24 h. Monte-Carlo simulation technique is used to estimate dose of particulate matter in probabilistic distribution by age and sex. The contribution of exposure by microenvironments and inhalation type was calculated. Risk assessment was performed based on WHO interim target-3 24-h concentration in order to estimate. Sensitivity analysis was performed to determine the effective variable of dose. As a result of the study, the dose of PM was higher for boys than girls and tended to decrease with age. The overall contributions of PM doses by microenvironments were daycare center, home, other facilities, transit, and outdoors, respectively, although differed between daycare center and home priority by age and sex. Especially, the contribution of daycare center and home was very high, accounting over 85% of the total. The overall contributions of PM doses by inhalation type were "run," "stable," "sleep," and "walk inhalation," respectively. The results of hazard quotient showed that "PM10" exceeded the WHO interim target-3 24-h concentration standard by about 10% and "PM2.5" exceeded about half. Through sensitivity analysis, PM concentration was confirmed as a major influence variable for doses. This study was able to affirm the overall exposure status of "PM10" and "PM2.5" for preschool children, and this is expected to be used in regulation and public health.
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http://dx.doi.org/10.1007/s11356-021-13106-2 | DOI Listing |
Res Child Adolesc Psychopathol
January 2025
Department of Psychology and the Florida Center for Reading Research, Florida State University, Tallahassee, FL, USA.
Despite frequent reliance on teacher and parent ratings of children's behavior for multi-informant assessment, agreement between teachers' and parents' ratings is low. This study examined the predictive utility of teacher and parent ratings for children's self-regulatory outcomes (i.e.
View Article and Find Full Text PDFBirth Defects Res
January 2025
School of Nursing, Ulster University Belfast, Belfast, Northern Ireland, UK.
Introduction: While improved medical and surgical care for children with pina bifida has improved their survival, some may have lower cognitive, behavioral and educational performance. The paper assesses the effect of spina bifida on cognitive, behavioral, and educational outcomes in 5-11 year olds.
Methods: A cross-sectional study design was used where data were collected from parents/guardians and teachers using Behavior Rating Inventory of Executive Function, second edition (BRIEF2), Strengths and Difficulties Questionnaire (SDQ), and Teacher Academic Attainment Scale (TAAS).
Zhongguo Dang Dai Er Ke Za Zhi
January 2025
Department of Pediatrics, Third People's Hospital of Longgang District of Shenzhen, Shenzhen, Guangdong 518020, China.
Objectives: To explore the role of berberine (BBR) in ameliorating coronary endothelial cell injury in Kawasaki disease (KD) by regulating the complement and coagulation cascade.
Methods: Human coronary artery endothelial cells (HCAEC) were divided into a healthy control group, a KD group, and a BBR treatment group (=3 for each group). The healthy control group and KD group were supplemented with 15% serum from healthy children and KD patients, respectively, while the BBR treatment group received 15% serum from KD patients followed by the addition of 20 mmol/L BBR.
Zhongguo Dang Dai Er Ke Za Zhi
January 2025
Department of Children's Hematology and Oncology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Objectives: To investigate the clinical characteristics and prognosis of acute erythroleukemia (AEL) in children.
Methods: A retrospective analysis was conducted on the clinical data, treatment, and prognosis of 8 children with AEL treated at the First Affiliated Hospital of Zhengzhou University from January 2013 to December 2023.
Results: Among the 7 patients with complete bone marrow morphological analysis, 4 exhibited trilineage dysplasia, with a 100% incidence of erythroid dysplasia (7/7), a 71% incidence of myeloid dysplasia (5/7), and a 57% incidence of megakaryocytic dysplasia (4/7).
Zhongguo Dang Dai Er Ke Za Zhi
January 2025
PICU, Huai'an Maternal and Child Health Hospital Affiliated to Yangzhou University, Huai'an, Jiangsu 223002, China.
Objectives: To investigate the expression of soluble factor-related apoptosis ligand (sFasL) in peripheral blood and microRNA-147b (miR-147b) in monocytes in children with sepsis and their value in assessing prognosis.
Methods: A prospective study was conducted on 124 children with sepsis (sepsis group), 60 children with common infections (infection group), and 60 healthy children undergoing physical examinations (healthy control group). The independent risk factors for poor prognosis in children with sepsis were analyzed, and the value of serum sFasL and monocyte miR-147b in predicting poor prognosis in children with sepsis was assessed.
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