Landsteiner's definition of human blood groups and the genetic rules that govern blood transfusion represents a milestone in human genetics and a historic event in public health. His research into the specificity of serological reactions, although less well known, has had a critical influence on the development of contemporary views on immune recognition, clonal selection, and immunological self-tolerance.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961596PMC
http://dx.doi.org/10.1084/jem.20202038DOI Listing

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