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Nebulized Hybrid Nanoarchaeosomes: Anti-Inflammatory Activity, Anti-Microbial Activity and Cytotoxicity on A549 Cells.
Int J Mol Sci
January 2025
Centro de Investigación y Desarrollo de Nanomedicinas (CIDeN), Departamento de Ciencia y Tecnología, Universidad Nacional de Quilmes, Roque Sáenz Peña 352, B1876 Bernal, Argentina.
The properties of two hybrid nanoarchaeosomes (hybrid nanoARCs) made of archaeolipids extracted from the halophilic archaea and combining the properties of archaeolipid bilayers with metallic nanoparticles are explored here. BS-nanoARC, consisting of a nanoARC loaded with yerba mate ( extract (YME)-biogenic silver nanoparticles (BSs), and [BS + BS-nanoARC], consistent of a BS-nanoARC core covered by an outer shell of BSs, were structurally characterized and their therapeutic activities screened. By employing 109 ± 5 µg gallic acid equivalents (GAEs) and 73.
View Article and Find Full Text PDFThe influence of phosphoinositide lipids in the molecular biology of membrane proteins: recent insights from simulations.
J Mol Biol
January 2025
Institute of Biological Chemistry, Academia Sinica, Taipei 115 Taiwan; Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QZ UK.
The phosphoinositide family of membrane lipids play diverse and critical roles in eukaryotic molecular biology. Much of this biological activity derives from interactions of phosphoinositide lipids with integral and peripheral membrane proteins, leading to modulation of protein structure, function, and cellular distribution. Since the discovery of phosphoinositides in the 1940s, combined molecular biology, biophysical, and structural approaches have made enormous progress in untangling this vast and diverse cellular network of interactions.
View Article and Find Full Text PDFEffects of the Dietary Blue-Green Algae (Spirulina platensis) Supplementation and Egg Storage Period on Egg Quality Traits, Blastoderm Characteristics and Hatching Results of Mast Geese (Anser anser).
J Anim Physiol Anim Nutr (Berl)
January 2025
Department of Animal Science, Faculty of Agriculture, Tekirdağ Namık Kemal University, Tekirdağ, Turkey.
This study aimed to determine the effects of the dietary Spirulina platensis supplementation and egg storage period on egg quality traits, blastoderm characteristics and hatching results of Mast geese. For this purpose, the control group was fed the standard enterprise diet, while the experimental group received the same diet supplemented with 0.5% S.
View Article and Find Full Text PDFImproving Real-Time Feedback During Cochlear Implantation: The Auditory Nerve Neurophonic/Cochlear Microphonic Ratio.
Ear Hear
January 2025
Department of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands.
Objectives: Real-time monitoring of cochlear function to predict the loss of residual hearing after cochlear implantation is now possible. Current approaches monitor the cochlear microphonic (CM) during implantation from the electrode at the tip of the implant. A drop in CM response of >30% is associated with poorer hearing outcomes.
View Article and Find Full Text PDFEvaluation and adaptation of a two-way text messaging intervention in the WIC breastfeeding peer counseling program: A qualitative analysis.
PLoS One
January 2025
Department of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, CT, United States of America.
Breastfeeding (BF) is vital for maternal and infant health, yet post-hospital discharge support remains a challenge. The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) provides BF peer counseling prenatally and up to 1-year postpartum among low-income women in the United States. The Lactation Advice Through Texting Can Help (LATCH) intervention is an evidence-based two-way text messaging intervention that provides BF education and support in the WIC peer counseling program.
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