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| http://dx.doi.org/10.11604/pamj.2020.36.224.24439 | DOI Listing |
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Objective: Aim: To give epidemiological and clinical characteristics of the morbidity of Lyme borreliosis in Ivano-Frankivsk region for the period of 2000-2022 years.
Patients And Methods: Materials and Methods: There were used annual reports (form №1) from the State Institution "Ivano-Frankivsk Regional Center for Disease Control and Prevention of the Ministry of Health of Ukraine" and 200 of "Medical records of inpatients" (form 003/о) of the Ivano-Frankivsk Regional Clinical Infectious Diseases Hospital for 2000-2022 years.
Results: Results: The morbidity of Lyme borreliosis in the Ivano-Frankivsk region has been permanently increasing since 2000.
What is "eczema"?
J Dermatol
September 2024
Department of Dermatology and Skin Oncology, Chutoen General Medical Center, Kakegawa, Japan.
Eczema is the most common category of inflammatory skin disorders as dermatologists see many patients with eczematous diseases in daily practice. It is characterized by the three major morphological features: multiple-pinpoint condition, polymorphism, and itch. To describe polymorphism, "eczema triangle" has been used in German/Japanese dermatology.
View Article and Find Full Text PDFAssociation of partial infections with the risk of psoriasis: A two-sample Mendelian randomization study.
Skin Res Technol
August 2024
Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine, Beijing, China.
Background: As a common chronic recurrent inflammatory skin disease, psoriasis is characterized by erythema and scaly skin lesions, with infection as an integral part of the pathogenesis of many diseases. Many previous cases reported the impact of psoriasis on infection. However, the existing research fails to completely clarify the infection factors associated with the potential of these diseases and causality.
View Article and Find Full Text PDFRecent progress in Stevens-Johnson syndrome/toxic epidermal necrolysis: diagnostic criteria, pathogenesis and treatment.
Br J Dermatol
December 2024
Division of Dermatology, Niigata University Graduate School of Medical and Dental Science, Niigata, Japan.
Article Synopsis
- Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe, rare skin reactions primarily triggered by drugs, leading to significant health risks and complications.
- The review suggests new diagnostic criteria to better identify these conditions and highlights recent research on how specific immune responses and genetic factors contribute to their development.
- It also discusses current and emerging treatment options, including debates on immunosuppressive therapies and new drug developments targeting specific mechanisms involved in SJS/TEN, advocating for a more collaborative approach in medical research to improve patient care.
Variants in the Late Cornified Envelope Gene Locus Are Associated With Elevated T-helper 17 Responses in Patients With Postinfectious Lyme Arthritis.
J Infect Dis
August 2024
Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York.
Background: Postinfectious Lyme arthritis (LA) is associated with dysregulated immunity and autoreactive T- and B-cell responses in joints. Here we explored the role of host genetic variation in this outcome.
Methods: The frequency of 253 702 single-nucleotide polymorphisms (SNPs) was determined in 147 patients with LA (87 with postinfectious LA and 60 with antibiotic-responsive LA), and for comparison in 90 patients with erythema migrans or the general population (n = 2504).
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