Non Malignant Lymphoproliferative Disorders in Children: A Case Series.

Indian J Hematol Blood Transfus

Department of Paediatric Haemato-Oncology, Kanchi Kamakoti Childs Trust Hospital, 12A Nageswara Road, Numgambakkam, Chennai, 600 034 India.

Published: January 2021

Lymphoproliferative disorders occurs due to uncontrolled proliferation of lymphocytes that causes lymphocytosis, lymphadenopathy, and involvement of extra nodal sites (bone marrow, liver and spleen) and occur primarily due to immune dysfunction. We describe series of cases with non malignant LPD encountered in our practice and their varied clinical presentation, difficulties in diagnosis, underlying etiology, treatment and outcome. Many of these disorders are self limiting, however some are associated with significant morbidity, hence treatment must be tailored based on the underlying immune dysfunction and aggressiveness of the clone.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7900327PMC
http://dx.doi.org/10.1007/s12288-020-01323-7DOI Listing

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