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Cells
December 2024
Department of Biochemistry, College of Medicine, Ewha Womans University, Seoul 07804, Republic of Korea.
In general, the nerve cells of the peripheral nervous system regenerate normally within a certain period after the physical damage of their axon. However, when peripheral nerves are transected by trauma or tissue extraction for cancer treatment, spontaneous nerve regeneration cannot occur. Therefore, it is necessary to perform microsurgery to connect the transected nerve directly or insert a nerve conduit to connect it.
View Article and Find Full Text PDFClin Physiol Funct Imaging
January 2025
Faculty of Medicine, Department Radiology, Gazi University, Ankara, Turkey.
Background: Optimizing hamstring exercises is crucial for injury prevention and performance. This study explored the effects of blood flow restriction (BFR) during Nordic hamstring exercises (NHE) on hamstring muscle activation and vascular function.
Methods: A randomized, single-blind study included 14 healthy, physically active males (mean age: 27.
Science
January 2025
Department of Otolaryngology, Department of Neuroscience and Physiology, and the Neuroscience Institute, NYU Grossman School of Medicine, New York, NY, USA.
Vertebrates stabilize gaze using a neural circuit that transforms sensed instability into compensatory counterrotation of the eyes. Sensory feedback tunes this vestibulo-ocular reflex throughout life. We studied the functional development of vestibulo-ocular reflex circuit components in the larval zebrafish, with and without sensation.
View Article and Find Full Text PDFJ Physiol
December 2024
Université Paris Cité, CNRS, ENS Paris Saclay, Centre Borelli UMR 9010, Paris, France.
Terminal Schwann cells (TSCs) are capable of regulating acetylcholine (ACh) release at the neuromuscular junction (NMJ). We have identified GABA as a gliotransmitter at mouse NMJs. When ACh activates α7 nicotinic ACh receptor (nAChRs) on TSCs, GABA is released and activates GABA receptors on the nerve terminal that subsequently reduce ACh release.
View Article and Find Full Text PDFJ Mol Histol
December 2024
The Second Clinical Medical College, Southern Medical University, Guangzhou City, Guangdong Province, 510515, China.
This study was to investigate the role of microRNA (miR)-330-5p derived from mesenchymal stem cells-secreted exosomes (MSCs-Exo) in cerebral ischemia-reperfusion injury (CI/RI) through targeting lysine N-methyltransferase SET domain containing 7 (SETD7). MSCs-Exo were separated and identified. MSCs-Exo were used to treat the middle cerebral artery occlusion (MCAO) rat model.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!