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Acellular Adipose Matrices Seem to Be an Effective and Safe Strategy for Soft Tissue Regeneration and Volume Restoration: A Systematic Review of Clinically Relevant Literature.
Adv Wound Care (New Rochelle)
January 2025
Division of Plastic Surgery, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
Autologous adipose tissue grafting (AAG) can provide soft tissue reconstruction in congenital defects, traumatic injuries, cancer care, or cosmetic procedures; over 94,000 AAG procedures are performed in the United States every year. Despite its effectiveness, the efficiency of AAG is limited by unpredictable adipocyte survival, impacting graft volume retention (26-83%). Acellular adipose matrices (AAMs) have emerged as a potential alternative to AAG.
View Article and Find Full Text PDFSimultaneous Profiling of Multiple Phosphorylated Metabolites in Typical Biological Matrices via Ion-Pair Reversed-Phase Ultrahigh-Performance Liquid Chromatography and Mass Spectrometry.
Anal Chem
January 2025
State Key Laboratory of Genetic Engineering, School of Life Sciences, Human Phenome Institute, Zhangjiang Fudan International Innovation Center, Metabonomics and Systems Biology Laboratory at Shanghai International Centre for Molecular Phenomics, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Simultaneous analysis of multiple phosphorylated metabolites (phosphorylated metabolome) in biological samples is vital to reveal their physiological and pathophysiological functions, which is extremely challenging due to their low abundance in some biological matrices, high hydrophilicity, and poor chromatographic behavior. Here, we developed a new method with ion-pair reversed-phase ultrahigh-performance liquid chromatography and mass spectrometry using BEH C18 columns modified with hybrid surface technology. This method demonstrated good performances for various phosphorylated metabolites, including phosphorylated sugars and amino acids, nucleotides, NAD-based cofactors, and acyl-CoAs in a single run using standard LC systems.
View Article and Find Full Text PDFBiological soil crusts (or biocrust) are diminutive soil communities with ecological functions disproportionate to their size. These communities are composed of lichens, bryophytes, cyanobacteria, fungi, liverworts, and other microorganisms. Creating stabilizing matrices, these microorganisms interact with soil surface minerals thereby enhancing soil quality by redistributing nutrients and reducing erosion by containment of soil particles.
View Article and Find Full Text PDFStudy of the release kinetics of Ethyl Lauroyl Arginate from poly(3-hydroxybutyrate-co-3-hydroxyvalerate) active films.
Food Res Int
January 2025
Department of Life Sciences, University of Modena and Reggio Emilia, Via Amendola 2, 42122 Reggio Emilia, Italy; Interdepartmental Research Centre for the Improvement of Agro-Food Biological Resources (BIOGEST-SITEIA), University of Modena and Reggio Emilia, Via Amendola 2, 42122 Reggio Emilia, Italy.
This study investigates the underexplored area of the release mechanism and kinetics of the antimicrobial Ethyl Lauroyl Arginate (LAE®) from an innovative active packaging system based on poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV). We evaluated the impact of food simulants and temperatures on LAE® release, diffusion, and partition coefficients. Mathematical modeling was used to elucidate LAE® release kinetics, offering understanding of the release behaviour in food matrices.
View Article and Find Full Text PDFCellulose Acetate Butyrate-Based In Situ Gel Comprising Doxycycline Hyclate and Metronidazole.
Polymers (Basel)
December 2024
Program of Pharmaceutical Engineering, Department of Industrial Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom 73000, Thailand.
Cellulose acetate butyrate is a biodegradable cellulose ester bioplastic produced from plentiful natural plant-based resources. Solvent-exchange-induced in situ gels are particularly promising for periodontitis therapy, as this dosage form allows for the direct delivery of high concentrations of antimicrobial agents to the localized periodontal pocket. This study developed an in situ gel for periodontitis treatment, incorporating a combination of metronidazole and doxycycline hyclate, with cellulose acetate butyrate serving as the matrix-forming agent.
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