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Prevention and Treatment of Neonatal Infections in Facility and Community Settings of Low- and Middle-Income Countries: A Descriptive Review.
Neonatology
November 2024
Centre for Global Child Health, Hospital for Sick Children, Toronto, Ontario, Canada.
Introduction: We present a robust and up-to-date synthesis of evidence on the effectiveness of interventions to prevent and treat newborn infections in low- and middle-income countries (LMICs). Newborn infection prevention interventions included strategies to reduce antimicrobial resistance (AMR), prevention of healthcare-associated infections (HAIs), clean birth kits (CBKs), chlorhexidine cleansing, topical emollients, and probiotic and synbiotic supplementation. Interventions to treat suspected neonatal infections included prophylactic systemic antifungal agents and community-based antibiotic delivery for possible serious bacterial infections (PSBIs).
View Article and Find Full Text PDFPlant Extract in the Control of Poultry Omphalitis.
Pathogens
May 2024
Laboratory of Poultry Science, Federal Institute of Brasília-Campus Planaltina, Brasília 73380-900, Brazil.
Bacteria continue to disrupt poultry production and can cause resistant and persistent yolk sac infections to prevention efforts, known as omphalitis, resulting in poultry death. This literature review aims to demonstrate how plant extracts can help combat omphalitis in poultry. The Google Scholar database served as a resource for retrieving pertinent literature covering a wide range of search terms relevant to the scope of the research.
View Article and Find Full Text PDFNational chlorhexidine coverage and factors associated with newborn umbilical cord care in Bangladesh and Nepal: a cross-sectional analysis using household data.
Matern Health Neonatol Perinatol
June 2024
School of Public Health and Community Medicine, University of Gothenburg, Gothenburg, Sweden.
Background: Preventable newborn deaths are a global tragedy with many of these deaths concentrated in the first week and day of life. A simple low-cost intervention, chlorhexidine cleansing of the umbilical cord, can prevent deaths from omphalitis, an infection of the umbilical cord. Bangladesh and Nepal have national policies promoting chlorhexidine use, as well as routinely collected household survey data, which allows for an assessment of coverage and predictors of the intervention.
View Article and Find Full Text PDFPrevalence, molecular characterization, and antimicrobial resistance among , spp., and strains isolated from Egyptian broiler chicken flocks with omphalitis.
Open Vet J
January 2024
Department of Poultry and Rabbit Diseases, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt.
Article Synopsis
- Bacterial Omphalitis is a significant cause of mortality in newly hatched broiler chicks, with a study in Gharbia, Egypt, revealing a 37.21% incidence rate among surveyed farms.
- The study characterized bacteria causing omphalitis and found high co-prevalence of multiple bacterial species in affected chicks.
- Key findings indicated drug resistance patterns, with isolates sensitive to gentamycin and tetracycline but showing significant resistance to several commonly used antibiotics, pointing to genetic factors contributing to this resistance.
Umbilical cord stump medication with a topical dermo protective powder compared to dry care in healthy full-term and near-term newborns: a two-center prospective cohort study.
Minerva Pediatr (Torino)
February 2024
Unit of Neonatal Intensive Care, V. Buzzi Children's Hospital, ASST-FBF-Sacco, Milan, Italy -
Background: Proper umbilical cord stump care during the first days of life (both in hospital and at home) should not be overlooked to prevent possible complications (e.g., purulent discharge, granulomas, or periumbilical erythema or omphalitis).
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