On 29 January 2021, we identified a new circulating lineage of Severe acute respiratory syndrome coronavirus 2 in Brazil, located in Sergipe state, Northeast region. The B.1.1.251 lineage was identified in a 32-old-man with headache, sore throat and coryza. Further studies are needed to evaluate the transmissibility and virulence of this emergent coronavirus lineage in Brazil.
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