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Case report: Dieulafoy's lesion as a rare cause of massive gastrointestinal hemorrhage.
Int J Surg Case Rep
December 2024
General Surgery Department, Mahmoud El Matri Hospital, V59M+628, Ariana, Tunisia; Faculty of Medicine of Tunis, University of Tunis El Manar, R534+F9H, Rue de la Faculté de Médecine, Tunis, Tunisia.
Introduction And Importance: Dieulafoy's lesion is a rare but serious cause of gastrointestinal bleeding, typically affecting older adults. It involves an aberrant arteriole eroding the gastric mucosa, resulting in severe, recurrent bleeding that poses diagnostic and management challenges. We present a case report of massive gastrointestinal hemorrhage with hemodynamic instability associated with a Dieulafoy's lesion.
View Article and Find Full Text PDFMassive lower gastrointestinal bleeding due to pseudoaneurysm of the femoral artery following buttock gunshot injury: A case report.
Int J Surg Case Rep
December 2024
Student Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Introduction: Arterio-enteric fistula is one of the extremely rare complications of penetrating trauma.
Case Presentation: A 27-year-old male presented to the emergency department with a gunshot to the right buttock. Initial assessments revealed a left femoral shaft fracture, the right buttock as the bullet inlet and the medial portion of the left thigh as an outlet, with no other significant findings.
Liver cancer multiomics reveals diverse protein kinase A disruptions convergently produce fibrolamellar hepatocellular carcinoma.
Nat Commun
December 2024
Laboratory of Cellular Biophysics, The Rockefeller University, New York, NY, USA.
Fibrolamellar Hepatocellular Carcinoma (FLC) is a rare liver cancer characterized by a fusion oncokinase of the genes DNAJB1 and PRKACA, the catalytic subunit of protein kinase A (PKA). A few FLC-like tumors have been reported showing other alterations involving PKA. To better understand FLC pathogenesis and the relationships among FLC, FLC-like, and other liver tumors, we performed a massive multi-omics analysis.
View Article and Find Full Text PDFRight Ventricular Myxoma Involving the Chordae Tendineae: A Case Report and Literature Review.
Cureus
November 2024
Department of Cardiothoracic Surgery, Castle Hill Hospital, Cottingham, GBR.
This case report describes a rare instance of massive right ventricular myxoma (RVM). A 36-year-old woman initially presented with progressive breathlessness and chest heaviness. Imaging revealed a large mass in the mediastinum, which was initially thought to be a pericardial cyst, and it was unclear whether the mass was intracardiac or extracardiac.
View Article and Find Full Text PDFAchievement of Clinical Remission in Life-Threatening Rosai-Dorfman Disease With Cladribine.
Cureus
November 2024
Hematology and Medical Oncology, Kettering Health, Kettering, USA.
Rosai-Dorfman disease (RDD) is a rare proliferative histiocytic disorder characterized by sinus histiocytosis with massive lymphadenopathy, rarely presenting with severe and life-threatening extra-nodal features. The rarity of RDD, clinically variant phenotype, limited data, and lack of a current standardized management approach make treatment decisions difficult. Herein, we present a case of life-threatening, disseminated RDD with rare clinical features of recurrent pericardial effusion, bilateral pleural effusions, and abdominal tissue fibrosis successfully treated with six cycles of cladribine, achieving clinical remission.
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