Feline noroviruses (FNoVs) are potential clinical pathogens in cats. To perform an epidemiological study of FNoV infection, it is necessary to develop a simple and effective method for virus detection. We investigated whether a commercial human NoV quantitative RT-PCR kit for the detection of human NoVs used in medical practice can be applied for FNoV detection. This kit was capable of detecting the FNoV gene regardless of the genogroup (GIV and GVI) in experimental and field samples. Based on the above findings, it is possible to detect FNoVs using human NoV tests. The relationship between FNoV infection and gastroenteritis in cats may be clarified by applying these methods to an epidemiological survey of FNoVs.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8182310PMC
http://dx.doi.org/10.1292/jvms.20-0703DOI Listing

Publication Analysis

Top Keywords

rt-pcr kit
8
fnov infection
8
human nov
8
detection
4
detection feline
4
feline norovirus
4
norovirus commercial
4
commercial real-time
4
real-time rt-pcr
4
kit diagnosis
4

Similar Publications

Wheat is an important cereal crop globally and in the United States, and is the largest crop grown by acreage in Colorado. In June 2023, we observed wheat fields displaying severe yellowing and virus-like disease symptoms in plants across seven eastern Colorado counties (Yuma, Prowers, Kit Carson, Washington, Sedgewick, Morgan, and Weld). Symptomatic plants were prominent in fields and appeared bright yellow, with ringspots, mosaic patterning, and streaking on leaves.

View Article and Find Full Text PDF

Background: Alzheimer's disease (AD) is a neurodegenerative disorder characterized by memory and cognitive impairments. Previous studies have shown neuronal death in the brains of AD patients, but the role of cuproptosis and its associated genes in AD neurons remains unclear.

Methods: Intersection analysis was conducted using the AD transcriptome dataset GSE63060, neuron dataset GSE147528, and reported cuproptosis-related genes to identify the cuproptosis key gene highly expressed in AD.

View Article and Find Full Text PDF

Arctiin alleviates the progression of osteoarthritis by regulating the cholesterol metabolic pathway.

Sci Rep

January 2025

Guangzhou First People's Hospital, the Second Affiliated Hospital, School of Medicine, South China University of Technology; Guangzhou First People's Hospital, Guangzhou Medical University, 1 Panfu Road, Yuexiu District, Guangzhou, 510180, China.

Osteoarthritis (OA) is a multi-factorial degenerative joint disease with unclear pathogenesis. Conservative treatments, primarily aimed at pain relief, fail to halt disease progression. Metabolic syndrome has recently been implicated in OA pathogenesis, underscoring the need for novel therapeutic strategies.

View Article and Find Full Text PDF

Deciphering the Prognostic Landscape of Esophageal Adenocarcinoma: A PANoptosis-Related Gene Signature.

J Cancer

January 2025

Department of Pathology, Nanjing Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, 210000, China.

Article Synopsis
  • Esophageal adenocarcinoma (EAC) has low survival rates despite treatment advancements, so understanding molecular mechanisms and identifying prognostic markers is essential for better patient outcomes.
  • A bioinformatics analysis identified 8 key PANoptosis-related genes (PRGs) to create a prognostic risk score model that outperformed traditional staging methods and was validated through multiple analyses, including gene expression profiling and immune infiltration assessment.
  • The study utilized techniques like WGCNA and RT-qPCR to identify crucial hub genes, whose effects on EAC cell behavior were tested in vitro, ultimately leading to a novel prognostic nomogram that integrates clinical features for improved predictive accuracy.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!