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Mifepristone versus Foley balloon catheter for outpatient cervical ripening at term: A non-inferiority randomised controlled trial.
Eur J Obstet Gynecol Reprod Biol
February 2025
Dep. Obstetrics and Gynecology, Medical School, University of Lisbon, Portugal; CEAUL - Centro de Estatística e Aplicações, Faculdade de Ciências, Universidade de Lisboa, Portugal.
Objective: To evaluate whether the success rate of oral mifepristone was not inferior to that of Foley balloon catheter for outpatient cervical ripening of term pregnancies, and whether there were differences in side effects for mothers and newborns.
Design: Open-label, non-inferiority randomised controlled trial.
Setting: A tertiary care European university hospital in an urban setting.
Efficacy of Dilapan S compared to foley balloon in preinduction cervical ripening-a noninferiority trial.
AJOG Glob Rep
November 2024
Department of Obstetrics and Gynaecology, PSGIMSR, Coimbatore, Tamil Nadu, India (Maheshwari).
Background: The need for induction of labor is increasing in present obstetric practice. The available non-pharmacological methods for cervical ripening at term are Foley balloon and Dilapan-S. With the gaining popularity of Dilapan-S worldwide, there are very few clinical trials conducted in India to evaluate its effectiveness.
View Article and Find Full Text PDFEffectiveness and Safety of the Double Intracervical Balloon vs Dinoprostone in Patients with Previous Cesarean Section.
Reprod Sci
October 2024
Department of Obstetrics and Gynecology, University Hospital Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Spain.
To compare effectiveness and safety of the Cook's balloon with vaginal dinoprostone to induce labor in patients with previous cesarean section. Observational, and retrospective study that included pregnant women at ≥ 37 weeks' gestation, with unfavorable cervix, singleton pregnancy, intact membranes, and a previous cesarean section, who had undergone labor induction in the period 2014-2019. 170 patients (86 balloon-84 dinoprostone) were analyzed.
View Article and Find Full Text PDFTime matters: Cervical ripening balloon for 6 versus 12 h-Retrospective comparison between two protocols.
Int J Gynaecol Obstet
August 2024
Department of Obstetrics and Gynecology, Bnai-Zion Medical Center, Haifa, Israel.
Objective: Recently, two randomized controlled trials compared removal of cervical ripening balloon (CRB) after 6 versus 12 h. Their results showed similar Bishop score changes in both groups and a shorter time to delivery in the 6-h group. Neither of the studies was powered to show difference in mode of delivery.
View Article and Find Full Text PDFMethods for the induction of labor: efficacy and safety.
Am J Obstet Gynecol
March 2024
Department of Obstetrics and Gynecology, University of Florida College of Medicine, Jacksonville, FL.
This review assessed the efficacy and safety of pharmacologic agents (prostaglandins, oxytocin, mifepristone, hyaluronidase, and nitric oxide donors) and mechanical methods (single- and double-balloon catheters, laminaria, membrane stripping, and amniotomy) and those generally considered under the rubric of complementary medicine (castor oil, nipple stimulation, sexual intercourse, herbal medicine, and acupuncture). A substantial body of published reports, including 2 large network meta-analyses, support the safety and efficacy of misoprostol (PGE1) when used for cervical ripening and labor induction. Misoprostol administered vaginally at doses of 50 μg has the highest probability of achieving vaginal delivery within 24 hours.
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