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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7958069 | PMC |
| http://dx.doi.org/10.2105/AJPH.2020.306150 | DOI Listing |
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Factors influencing vaccine hesitancy among United Kingdom adolescents in a senior high school environment and actions to address it.
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We explored adolescent viewpoints on vaccines and hesitancy using an anonymized, validated, self-completed electronic questionnaire amongst state-school Year 12-13 adolescents in London, UK. As the response rate was low (Cohort 1; = 112/486, 23.0%), we repeated the survey with incoming students (cohort 2, = 256/275; 93%).
View Article and Find Full Text PDFLyophilized monkeypox mRNA lipid nanoparticle vaccines with long-term stability and robust immune responses in mice.
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Department of Research & Development, Yither Biotech Co Ltd, Shanghai, China.
The World Health Organization (WHO) has recently declared another global health emergency due to the rapidly spreading monkeypox (Mpox) outbreak in numerous African countries. To address the unmet need to contain the outbreak using the existing vaccines, this study developed a lyophilization process for an effective, scalable and affordable Mpox mRNA-LNP vaccine candidate to address the global health crisis. A comprehensive evaluation and optimization of the vaccine formulation (the type/concentration of cryoprotectants, the type/concentration of buffer system, as well as the mRNA concentration and reconstitution solvent) and the freeze-drying process parameters (freezing method, temperature, cooling rate and primary/secondary drying conditions) were conducted.
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Evaluating the Inhibitory Effects of Probiotic Bacteria and Propolis Extracts on the Growth and Histopathological Changes in Gastric Tissues of Challenged Wistar Rats.
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Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Background: is a significant contributor to a range of gastrointestinal conditions, with conventional treatment methods primarily relying on antibiotics. However, the rise of antibiotic-resistant strains has necessitated the exploration of alternative therapeutic approaches.
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