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| http://dx.doi.org/10.23750/abm.v92i1.9450 | DOI Listing |
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The Endoscopic Management of Zenker's Diverticulum: A Comprehensive Review.
Diagnostics (Basel)
September 2024
Gastroenterology and Gastrointestinal Endoscopy Division, IRCCS San Raffaele Institute, Via Olgettina 60, 20132 Milan, Italy.
Article Synopsis
- Zenker's Diverticulum (ZD) is a common throat condition caused by a herniation of tissue, leading to difficulty swallowing (dysphagia) in most patients.
- Traditional surgery for ZD has high technical challenges and can result in significant complications, prompting interest in less invasive endoscopic methods.
- Newer endoscopic techniques like Zenker-POEM and Per Oral Endoscopic Septomyotomy offer alternative treatment options, which are discussed along with their pros, cons, and potential future developments.
Factors Associated with Mother's Own Milk Feeding and Direct Breastfeeding at Discharge in Preterm Infants with Feeding Difficulties: Clinical and Research Implications.
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November 2024
The Innovative Infant Feeding Disorders Research Program, Nationwide Children's Hospital, Columbus, Ohio, USA.
Prematurity presents numerous barriers to mother's own milk (MOM) feeding and direct breastfeeding (DBF). This study aimed to determine factors associated with MOM feeding and DBF at discharge from the neonatal intensive care unit (NICU) in preterm-born infants presenting with feeding difficulties. A retrospective study of data from 237 preterm-born infants referred for evaluation of feeding difficulties and discharged home on full oral feeds was examined.
View Article and Find Full Text PDFFluorine-MRI Based Longitudinal Immuno-Microenvironment-Monitoring for Pancreatic Cancer.
J Magn Reson Imaging
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German Cancer Consortium (DKTK), Partner Site Freiburg, Freiburg, Germany.
Background: Pancreatic cancer has a poor prognosis. Targeting Kirsten Rat Sarcoma (KRAS) mutation and its related pathways may enhance immunotherapy efficacy. While in vivo monitoring of therapeutic response and immune cell migration remains challenging, Fluorine-19 MRI (F MRI) may allow noninvasive longitudinal imaging of immune cells.
View Article and Find Full Text PDFEsophageal Per-Oral Endoscopic Myotomy (E-POEM): Future Directions and Perspectives.
Curr Gastroenterol Rep
October 2024
Division of Gastroenterology and Hepatology, University of Florida, PO Box 100214, Gainesville, FL, 32610, USA.
Purpose Of Review: POEM is a mature procedure endorsed by societal guidelines as a first line therapy for achalasia and spastic esophageal disorders. Nonetheless, several questions remain, including expanding indications for POEM, periprocedural evaluation and management, and the optimal POEM technique to enhance clinical success while mitigating risk for reflux.
Recent Findings: There is uncertainty regarding several technical aspects of the POEM myotomy; though aggregating evidence supports the use of real-time impedance planimetry to guide the myotomy.
Esophageal impedance planimetry during per-oral endoscopic myotomy guides myotomy extent.
Surg Endosc
September 2024
Department of Surgery, The MetroHealth System, 2500 MetroHealth Drive, Cleveland, OH, 44109, USA.
Introduction: Peroral endoscopic myotomy (POEM) is the standard treatment for achalasia. Functional luminal imaging probe (FLIP) technology enables objective measurement of lower esophageal sphincter (LES) geometry, with literature linking specific values to improved post-POEM outcomes. Our study assesses FLIP's intraoperative use in evaluating myotomy extent in real-time.
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